Microbiota and Diapause-Induced Neuroprotection Share a Dependency on Calcium But Differ in Their Effects on Mitochondrial Morphology
Delgado S, Urrutia A, Gutzwiller F, Chiu C, Calixto A. Microbiota and Diapause-Induced Neuroprotection Share a Dependency on Calcium But Differ in Their Effects on Mitochondrial Morphology. ENeuro 2023, 10: eneuro.0424-22.2023. PMID: 37385728, PMCID: PMC10368204, DOI: 10.1523/eneuro.0424-22.2023.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCaenorhabditis elegansCalciumDiapauseGastrointestinal MicrobiomeMitochondriaNeuroprotectionConceptsCaenorhabditis elegans</i>Length of mitochondriaDiapause entryLactate-producing bacteriaReverse geneticsGut microbiotaMitochondrial morphologyTranscriptomic approachMitochondrial sizeMitochondrial functionMicrobiotaMechanistic commonalitiesEnvironmental variablesBacteriaMCU-1GenesNeuronal functionMultiple mechanismsCalcium homeostasisDiapauseNeuronal degenerationNeuronal protectionRegeneration of damaged neuronsFood deprivationTranscriptome