2023
Disorder of Golgi Apparatus Precedes Anoxia-Induced Pathology of Mitochondria
Morozov Y, Rakic P. Disorder of Golgi Apparatus Precedes Anoxia-Induced Pathology of Mitochondria. International Journal Of Molecular Sciences 2023, 24: 4432. PMID: 36901863, PMCID: PMC10003327, DOI: 10.3390/ijms24054432.Peer-Reviewed Original ResearchConceptsGolgi apparatusH anoxiaPost-translational protein modificationStomatin-like protein 2Role of mitochondriaEmbryonic mouse brainEmbryonic mouse brain cellsGolgi architectureSecretory traffickingMitochondrial matrixProtein modificationMouse brain cellsMitochondrial malfunctionTrans cisternaeBrain cellsMitochondriaOrganellesProtein 2Mitochondrial disordersLateral ganglionic eminenceEarly eventsComplex pathological changesMouse brainNormal ultrastructureGanglionic eminence
2016
Ultrastructural evidence for impaired mitochondrial fission in the aged rhesus monkey dorsolateral prefrontal cortex
Morozov YM, Datta D, Paspalas CD, Arnsten AF. Ultrastructural evidence for impaired mitochondrial fission in the aged rhesus monkey dorsolateral prefrontal cortex. Neurobiology Of Aging 2016, 51: 9-18. PMID: 28027494, PMCID: PMC5292282, DOI: 10.1016/j.neurobiolaging.2016.12.001.Peer-Reviewed Original Research
2015
Alteration of SLP2‐like immunolabeling in mitochondria signifies early cellular damage in developing and adult mouse brain
Morozov YM, Sun YY, Kuan CY, Rakic P. Alteration of SLP2‐like immunolabeling in mitochondria signifies early cellular damage in developing and adult mouse brain. European Journal Of Neuroscience 2015, 43: 245-257. PMID: 26547131, PMCID: PMC4784115, DOI: 10.1111/ejn.13124.Peer-Reviewed Original ResearchConceptsStomatin-like protein 2Inner mitochondrial membrane protein complexMitochondrial membrane protein complexesMembrane protein complexesInner mitochondrial membraneRegulated cell deathAmino acid sequenceLinear amino acid sequenceCellular damageProtein complexesMitochondrial matrixAdult mouse brainMitochondrial membraneAcid sequenceMitochondrial biogenesisMouse brainHuman diseasesAnti-CB1 antibodyCell deathMitochondriaMitochondrial dysfunctionNeuronal cellsProtein 2Normal mitochondriaSelective labeling
2013
Antibodies to cannabinoid type 1 receptor co‐react with stomatin‐like protein 2 in mouse brain mitochondria
Morozov YM, Dominguez MH, Varela L, Shanabrough M, Koch M, Horvath TL, Rakic P. Antibodies to cannabinoid type 1 receptor co‐react with stomatin‐like protein 2 in mouse brain mitochondria. European Journal Of Neuroscience 2013, 38: 2341-2348. PMID: 23617247, PMCID: PMC3902808, DOI: 10.1111/ejn.12237.Peer-Reviewed Original ResearchConceptsStomatin-like protein 2Type 1 receptorPresence of CB1Protein 2Anti-CB1 antibodySynthetic cannabinoid WINMouse brain mitochondriaCerebral cortexEndocannabinoid signalingBrain cellsCannabinoid WINNeuronal mitochondriaBrain mitochondriaAntibodiesMitochondrial functionCB1Polyclonal antibodiesCortexMitochondrial preparationsSerumReceptors