Leukemia Inhibitory Factor Determines the Growth Status of Injured Adult Sensory Neurons
Cafferty W, Gardiner N, Gavazzi I, Powell J, McMahon S, Heath J, Munson J, Cohen J, Thompson S. Leukemia Inhibitory Factor Determines the Growth Status of Injured Adult Sensory Neurons. Journal Of Neuroscience 2001, 21: 7161-7170. PMID: 11549727, PMCID: PMC6762988, DOI: 10.1523/jneurosci.21-18-07161.2001.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAxotomyCalcitonin Gene-Related PeptideCell DivisionCell SurvivalCells, CulturedCytoprotectionFemaleGanglia, SpinalGrowth InhibitorsInjections, SpinalInterleukin-6Leukemia Inhibitory FactorLymphokinesMaleMiceMice, KnockoutNerve FibersNerve RegenerationNeuritesNeurons, AfferentPhenotypeRatsRats, WistarSciatic NerveTibial NerveConceptsLeukemia inhibitory factorLIF-/- miceAdult sensory neuronsSensory neuronsConditioning injuryInhibitory factorPeptidergic sensory neuronsMammalian sensory neuronsIntrinsic growth capacityExogenous leukemia inhibitory factorNerve damageReceptor antagonistNeuronsConditioning responseNeurite outgrowthInjuryGrowth statusVivoNormal regenerationStatusAntagonistGrowth capacityMice