2001
CASK and Protein 4.1 Support F-actin Nucleation on Neurexins*
Biederer T, Südhof T. CASK and Protein 4.1 Support F-actin Nucleation on Neurexins*. Journal Of Biological Chemistry 2001, 276: 47869-47876. PMID: 11604393, DOI: 10.1074/jbc.m105287200.Peer-Reviewed Original ResearchMeSH KeywordsActinsAmino Acid SequenceAnimalsBinding SitesCalcium-Calmodulin-Dependent Protein KinasesCytoplasmCytoskeletal ProteinsGlycophorinsGuanylate KinasesMembrane ProteinsMolecular Sequence DataNerve Tissue ProteinsNeuropeptidesNucleoside-Phosphate KinaseProtein BindingRatsSequence Homology, Amino AcidSpectrinConceptsProtein 4.1Actin cytoskeletonActin filamentsBrain-enriched isoformF-actin nucleationCytosolic C-terminusClass of proteinsCell surface proteinsCytosolic tailPDZ domainAdaptor proteinCellular processesMembrane organizationC-terminusNeurexinsProtein p55Glycophorin CCell surfaceRat brain extractsIntercellular junctionsSpectrin filamentsErythrocyte isoformsCytoskeletonProteinLocomotion of cells
2000
Mints as Adaptors DIRECT BINDING TO NEUREXINS AND RECRUITMENT OF Munc18*
Biederer T, Südhof T. Mints as Adaptors DIRECT BINDING TO NEUREXINS AND RECRUITMENT OF Munc18*. Journal Of Biological Chemistry 2000, 275: 39803-39806. PMID: 11036064, DOI: 10.1074/jbc.c000656200.Peer-Reviewed Original ResearchConceptsAdaptor proteinPDZ domain-mediated interactionsDomain-mediated interactionsSynaptic vesicle exocytosisCell surface proteinsNeuronal adaptor proteinMultiprotein complexesProtein essentialCytoplasmic tailMunc18-1Vesicle exocytosisPlasma membraneMunc18NeurexinsDirect bindingPossible functionsSurface proteinsProteinExocytosisMINT1RecruitmentComplexesMint2BindsMint