2013
The fat mass and obesity associated gene (Fto) regulates activity of the dopaminergic midbrain circuitry
Hess ME, Hess S, Meyer KD, Verhagen LA, Koch L, Brönneke HS, Dietrich MO, Jordan SD, Saletore Y, Elemento O, Belgardt BF, Franz T, Horvath TL, Rüther U, Jaffrey SR, Kloppenburg P, Brüning JC. The fat mass and obesity associated gene (Fto) regulates activity of the dopaminergic midbrain circuitry. Nature Neuroscience 2013, 16: 1042-1048. PMID: 23817550, DOI: 10.1038/nn.3449.Peer-Reviewed Original ResearchMeSH KeywordsAdenineAlpha-Ketoglutarate-Dependent Dioxygenase FTOAnimalsCocaineCorpus StriatumDopamineDopaminergic NeuronsExploratory BehaviorFemaleG Protein-Coupled Inwardly-Rectifying Potassium ChannelsLocomotionMaleMesencephalonMethylationMethyltransferasesMiceMice, Inbred C57BLMice, KnockoutMixed Function OxygenasesOxo-Acid-LyasesPhenotypeQuinpiroleReceptors, Dopamine D2Receptors, Dopamine D3RewardRNA Processing, Post-TranscriptionalRNA, MessengerSignal Transduction
2009
Correlation between body weight changes and postoperative pain in rats treated with meloxicam or buprenorphine
Brennan MP, Sinusas AJ, Horvath TL, Collins JG, Harding MJ. Correlation between body weight changes and postoperative pain in rats treated with meloxicam or buprenorphine. Lab Animal 2009, 38: 87-93. PMID: 19229225, PMCID: PMC2805902, DOI: 10.1038/laban0309-87.Peer-Reviewed Original ResearchConceptsPostoperative painBody weightAdult male Lewis ratsWeight changeMajor surgical proceduresGeneral endotracheal anesthesiaMale Lewis ratsEfficacy of meloxicamRat body weightYoung adult ratsBody weight changesBody weight gainBuprenorphine analgesiaPostoperative changesLewis ratsEndotracheal anesthesiaSurgical proceduresPhysiologic effectsAdult ratsControl groupPainBuprenorphineRatsNormal levelsWeight gain