2009
Differentiation of Neural Progenitor Cells in a Microfluidic Chip‐Generated Cytokine Gradient
Park J, Kim S, Woo D, Lee E, Kim J, Lee S. Differentiation of Neural Progenitor Cells in a Microfluidic Chip‐Generated Cytokine Gradient. Stem Cells 2009, 27: 2646-2654. PMID: 19711444, DOI: 10.1002/stem.202.Peer-Reviewed Original ResearchConceptsCell typesNeural progenitorsHuman embryonic stem cellsEarly embryonic developmentStem cellsEmbryonic stem cellsCytokine gradientsEnriched populationNeural progenitor cellsPrimitive stem cellsEmbryonic developmentSignaling moleculesDiverse tissuesCell body clustersProgenitor cellsNeurite bundlesGrowth factorProgenitorsCell-friendly microenvironmentCellsDifferentiationExogenous cytokinesImportant roleBody clustersSpatial gradientsDifferentiation of Human Neural Progenitor Cells on PLGA Microfibers
Hwang C, Kim S, Kim J, Khademhosseini A, Lee S. Differentiation of Human Neural Progenitor Cells on PLGA Microfibers. 2009, 1: 1-2. DOI: 10.1109/nebc.2009.4967758.Peer-Reviewed Original ResearchHuman embryonic stem cellsNeural progenitor cellsEmbryoid bodiesMicrofluidic spinning systemPLGA microfibersNeural tissue regenerationEmbryonic stem cellsNeural tissue engineeringProgenitor cellsHuman neural progenitor cellsTissue engineeringNeuronal protein expressionNeural progenitor markersGlial fibrillary acidic proteinMicrofibersTissue regenerationNascent fibersPLGA fibersNeural progenitorsDifferentiated cellsCell differentiationProgenitor markersStem cellsGuidance cuesProtein expression
2006
Neurogenic effect of vascular endothelial growth factor during germ layer formation of human embryonic stem cells
Kim B, Kim S, Shim J, Woo D, Gil J, Kim S, Kim J. Neurogenic effect of vascular endothelial growth factor during germ layer formation of human embryonic stem cells. FEBS Letters 2006, 580: 5869-5874. PMID: 17027979, DOI: 10.1016/j.febslet.2006.09.053.Peer-Reviewed Original ResearchConceptsHuman embryonic stem cellsVascular endothelial growth factorGerm layer formationEmbryonic stem cellsEmbryoid bodiesEndothelial growth factorNeurogenic effectsGrowth factorStem cellsEffects of VEGFNeuroectodermal genesVascular endothelial cellsHESC differentiationNeural rosettesDopaminergic neuronsGene expressionNeural progenitorsTerminal differentiationVEGF treatmentPotent mitogenEndothelial cellsNeuroectodermal differentiationDifferentiationCellsExpression