2003
Delayed Systemic Nogo-66 Receptor Antagonist Promotes Recovery from Spinal Cord Injury
Li S, Strittmatter SM. Delayed Systemic Nogo-66 Receptor Antagonist Promotes Recovery from Spinal Cord Injury. Journal Of Neuroscience 2003, 23: 4219-4227. PMID: 12764110, PMCID: PMC6741116, DOI: 10.1523/jneurosci.23-10-04219.2003.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsAxonsAxotomyBehavior, AnimalCornified Envelope Proline-Rich ProteinsFemaleGanglia, SpinalGPI-Linked ProteinsInjections, SubcutaneousIntralaminar Thalamic NucleiMembrane ProteinsMiceMice, Inbred C57BLMolecular Sequence DataMolecular WeightMotor ActivityMyelin ProteinsNerve FibersNerve RegenerationNogo Receptor 1Peptide FragmentsProtein BiosynthesisProteinsPyramidal TractsReceptors, Cell SurfaceSerotoninSpinal CordSpinal Cord InjuriesConceptsSpinal cord injuryCord injuryCorticospinal axonsThoracic spinal cord injuryTherapeutic time windowSpinal cord hemisectionSpinal cord traumaCorticospinal tract axonsAdult mammalian CNSNogo-66 receptorOligodendrocyte myelin glycoproteinCNS axonal injuryCord lesionsSubcutaneous treatmentSystemic therapyCord hemisectionCord traumaIntrathecal applicationLocal therapyLocomotor recoveryFunctional recoverySerotonergic fibersAxonal injuryReceptor antagonistAxon sprouting
1996
P2Y1 purinergic receptors in sensory neurons: contribution to touch-induced impulse generation.
Nakamura F, Strittmatter SM. P2Y1 purinergic receptors in sensory neurons: contribution to touch-induced impulse generation. Proceedings Of The National Academy Of Sciences Of The United States Of America 1996, 93: 10465-10470. PMID: 8816824, PMCID: PMC38408, DOI: 10.1073/pnas.93.19.10465.Peer-Reviewed Original ResearchMeSH KeywordsAdenosine TriphosphateAnimalsApyraseChickensFemaleGanglia, SpinalMembrane PotentialsMolecular Sequence DataNerve FibersNeurons, AfferentOocytesPhysical StimulationPurinergic P2 Receptor AgonistsPyridoxal PhosphateRatsReceptors, Purinergic P2Receptors, Purinergic P2X3Receptors, Purinergic P2Y1RNA, MessengerSciatic NerveSkinSuraminTime FactorsTranscription, GeneticXenopus laevisConceptsNerve endingsPurinergic receptorsSensory neuronsAction potentialsSmall fiber sensory neuronsDorsal root ganglion neuronsDistal nerve endingsSensory action potentialsPeripheral nerve endingsSensory nerve fibersP2 receptor agonistsP2Y1 purinergic receptorRelease of ATPP2 antagonistsGanglion neuronsReceptor agonistNerve fibersLight touchNeuronsXenopus laevis oocytesSomatic sensationsReceptorsImpulse generationExtracellular spaceLaevis oocytes