1997
Brain CRMP Forms Heterotetramers Similar to Liver Dihydropyrimidinase
Wang L, Strittmatter S. Brain CRMP Forms Heterotetramers Similar to Liver Dihydropyrimidinase. Journal Of Neurochemistry 1997, 69: 2261-2269. PMID: 9375656, DOI: 10.1046/j.1471-4159.1997.69062261.x.Peer-Reviewed Original Research
1996
Signal Transduction at the Neuronal Growth Cone
Strittmatter S. Signal Transduction at the Neuronal Growth Cone. The Neuroscientist 1996, 2: 83-86. DOI: 10.1177/107385849600200208.Peer-Reviewed Original ResearchSignal transductionG-protein-mediated transductionG proteinsHeterotrimeric G proteinsCell adhesion molecule familyGrowth conesNervous system developmentAdhesion molecule familyGrowth cone membraneNeuronal growth conesLigand-receptor interactionsGrowth cone motilityCadherin familyIntracellular proteinsCytoskeletal changesExtracellular moleculesMolecular understandingIntegrin familyTransductionMolecules inhibitoryDiffusible messengerMolecule familyCone motilityIntracellular eventsCone membrane
1995
Neuronal pathfinding is abnormal in mice lacking the neuronal growth cone protein GAP-43
Strittmatter S, Fankhauser C, Huang P, Mashimo H, Fishman M. Neuronal pathfinding is abnormal in mice lacking the neuronal growth cone protein GAP-43. Cell 1995, 80: 445-452. PMID: 7859286, DOI: 10.1016/0092-8674(95)90495-6.Peer-Reviewed Original Research
1994
Activated mutants of the alpha subunit of G(o) promote an increased number of neurites per cell
Strittmatter S, Fishman M, Zhu X. Activated mutants of the alpha subunit of G(o) promote an increased number of neurites per cell. Journal Of Neuroscience 1994, 14: 2327-2338. PMID: 8158271, PMCID: PMC6577129, DOI: 10.1523/jneurosci.14-04-02327.1994.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsBase SequenceCell LineChlorocebus aethiopsDNA PrimersDose-Response Relationship, DrugGTP-Binding ProteinsIntercellular Signaling Peptides and ProteinsKineticsMacromolecular SubstancesMolecular Sequence DataMutagenesis, Site-DirectedNeuritesNeuroblastomaPC12 CellsPeptidesPertussis ToxinPoint MutationTransfectionTumor Cells, CulturedVirulence Factors, BordetellaWasp VenomsConceptsAlpha oNumber of neuritesPertussis toxin-sensitive G proteinToxin-sensitive G proteinGrowth conesAlpha subunitG proteinsNeurite outgrowthTotal neurite lengthN1E-115 cellsAlpha i2Activated alpha subunitNeuroblastoma cellsNeurite numberNeurite lengthNeuronal growth conesAlpha sOncogenic mutationsActivation stateO mutantsActivationNeuritesCellsPoint mutationsSubunits
1991
The neuronal growth cone as a specialized transduction system
Strittmatter S, Fishman M. The neuronal growth cone as a specialized transduction system. BioEssays 1991, 13: 127-134. PMID: 1831353, DOI: 10.1002/bies.950130306.Peer-Reviewed Original ResearchConceptsGene programGrowth conesNeuronal growth conesExtracellular stimuliEnvironmental signalsExtracellular signalsMembrane proteinsTransduction systemCell shapeGrowth cone behaviorExtracellular matrixGrowth cone activityCone behaviorGrowth programMechanical forcesNeuronal growthProteinTransduction devicesIntrinsic factorsGAP-43Molecular sitesGTPPossible componentsSitesCone activityGrowth cone transduction: Go and GAP-43
STRITTMATTER S, VALENZUELA D, VARTANIAN T, SUDO Y, ZUBER M, FISHMAN M. Growth cone transduction: Go and GAP-43. Journal Of Cell Science. Supplement 1991, 1991: 27-33. PMID: 1840457, DOI: 10.1242/jcs.1991.supplement_15.5.Peer-Reviewed Original ResearchConceptsGrowth cone membraneExtracellular signalsIntracellular proteinsGrowth cone targetingNon-cytoskeletal proteinsG protein familyG-protein-linked receptorsAppropriate synaptic targetsComplex brain architectureCone membraneGrowth conesProtein-linked receptorsGrowth cone functionNeuronal growth conesMembrane associationProtein familyNon-neuronal cellsGAP-43Filopodial formationAmino terminusCell shapeExtrinsic cluesSecond messengerGrowth proteinsProtein