2000
Mechanisms of programmed cell death in the developing brain
Kuan C, Roth K, Flavell R, Rakic P, Kuan C, Roth K, Flavell R, Rakic P. Mechanisms of programmed cell death in the developing brain. Trends In Neurosciences 2000, 23: 291-297. PMID: 10856938, DOI: 10.1016/s0166-2236(00)01581-2.Peer-Reviewed Original ResearchConceptsCell deathNematode Caenorhabditis elegansEarly embryonic developmentGene-targeting studiesCell death pathwaysVertebrate nervous systemMammalian brain developmentCaenorhabditis elegansEmbryonic developmentGenetic analysisPostmitotic neuronsBrain developmentNeural cell deathAnalogous functionsDistinct rolesProgenitor cellsMammalian brainApoptosisNew insightsImportant mechanismElegansHomologLater stagesNervous systemMechanism
1991
Critical Cellular Events During Cortical Evolution: Radial Unit Hypothesis
Rakic P. Critical Cellular Events During Cortical Evolution: Radial Unit Hypothesis. NATO Science Series A: 1991, 21-32. DOI: 10.1007/978-1-4899-0652-6_3.Peer-Reviewed Original ResearchCell biological mechanismsCritical cellular eventsComplex cellular changesCellular eventsRadial unit hypothesisCerebral evolutionCortical evolutionCellular mechanismsCellular changesBiological mechanismsRemarkable structureHuman mental capacitiesEvolutionMechanismContemporary neuroscientistsPrimates