2000
Basic Fibroblast Growth Factor (Fgf2) Is Necessary for Cell Proliferation and Neurogenesis in the Developing Cerebral Cortex
Raballo R, Rhee J, Lyn-Cook R, Leckman J, Schwartz M, Vaccarino F. Basic Fibroblast Growth Factor (Fgf2) Is Necessary for Cell Proliferation and Neurogenesis in the Developing Cerebral Cortex. Journal Of Neuroscience 2000, 20: 5012-5023. PMID: 10864959, PMCID: PMC6772267, DOI: 10.1523/jneurosci.20-13-05012.2000.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsApoptosisCell DivisionCerebral CortexChoroid PlexusEmbryonic and Fetal DevelopmentFibroblast Growth Factor 2Gene Expression Regulation, DevelopmentalGerm-Line MutationGestational AgeMiceMice, KnockoutProsencephalonReceptor Protein-Tyrosine KinasesReceptor, Fibroblast Growth Factor, Type 1Receptors, Fibroblast Growth FactorTelencephalonConceptsFgf2 knockout micePseudostratified ventricular epitheliumKnockout miceCerebral cortexCortical neuronsFrontal cerebral cortexDeep cortical layersBasic fibroblast growth factorEnd of neurogenesisCortical neuron numberNeuronal progenitor cellsNull mutant miceBasic fibroblast growth factor (bFGF) geneFibroblast growth factorDegree of apoptosisLarge neuronsBasal gangliaCortical layersFgf2 knockoutGrowth factor geneMutant miceVentricular epitheliumGermline mutationsNeuron numberNeurogenesis
1999
Changes in cerebral cortex size are governed by fibroblast growth factor during embryogenesis
Vaccarino F, Schwartz M, Raballo R, Nilsen J, Rhee J, Zhou M, Doetschman T, Coffin J, Wyland J, Hung Y. Changes in cerebral cortex size are governed by fibroblast growth factor during embryogenesis. Nature Neuroscience 1999, 2: 246-253. PMID: 10195217, DOI: 10.1038/6350.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCerebral CortexEmbryo, MammalianEmbryonic and Fetal DevelopmentFibroblast Growth Factor 2Fibroblast Growth FactorsMiceMice, KnockoutMicroinjectionsRatsStem CellsConceptsPseudostratified ventricular epitheliumFibroblast growth factor-2Number of gliaAdult cerebral cortexEnd of neurogenesisCerebral cortex sizeFibroblast growth factorGrowth factor 2Cerebral cortexCerebral ventricleSingle microinjectionCortical neuronsBrdU studiesCortical progenitorsVentricular epitheliumCortex sizeGrowth factorRat embryosFGF2 geneEarly neurogenesisFGF receptorsFactor 2GliaNeurogenesisCell cycle length
1992
Early Expression of GABA-containing Neurons in the Prefrontal and Visual Cortices of Rhesus Monkeys
Schwartz M, Meinecke D. Early Expression of GABA-containing Neurons in the Prefrontal and Visual Cortices of Rhesus Monkeys. Cerebral Cortex 1992, 2: 16-37. PMID: 1633406, DOI: 10.1093/cercor/2.1.16.Peer-Reviewed Original ResearchConceptsSubplate zoneCortical neuronsRhesus monkeysDensity of GABADistribution of GABAPrimary sensory regionsFirst postnatal weekElectron microscopic immunohistochemistryImmunoreactive neuronsCerebral cortexTransmitter phenotypeCortical maturationCortical plateBipolar neuronsSubventricular zonePostnatal weekCerebral wallCortical neurogenesisVisual cortexMature monkeysVentricular zoneGABASynaptic interactionsDay 41Neurons