2009
Consequences of axon guidance defects on the development of retinotopic receptive fields in the mouse colliculus
Chandrasekaran AR, Furuta Y, Crair MC. Consequences of axon guidance defects on the development of retinotopic receptive fields in the mouse colliculus. The Journal Of Physiology 2009, 587: 953-963. PMID: 19153163, PMCID: PMC2673768, DOI: 10.1113/jphysiol.2008.160952.Peer-Reviewed Original ResearchConceptsSuperior colliculusMutant miceBone morphogenetic protein receptorRetinal ganglion cell axonsGuidance moleculesSpontaneous retinal wavesGanglion cell axonsSuperficial superior colliculusReceptive field propertiesRetinotopic receptive fieldsActivity-dependent factorsMore RGCsRetinocollicular projectionRetinal wavesEctopic projectionsVentral retinaCell axonsRetinotopic map formationAnatomical defectsAction potentialsActivity-dependent learning ruleSpontaneous wavesRetinaRGCsMice
2008
Bone Morphogenetic Proteins, Eye Patterning, and Retinocollicular Map Formation in the Mouse
Plas DT, Dhande OS, Lopez JE, Murali D, Thaller C, Henkemeyer M, Furuta Y, Overbeek P, Crair MC. Bone Morphogenetic Proteins, Eye Patterning, and Retinocollicular Map Formation in the Mouse. Journal Of Neuroscience 2008, 28: 7057-7067. PMID: 18614674, PMCID: PMC2667968, DOI: 10.1523/jneurosci.3598-06.2008.Peer-Reviewed Original ResearchConceptsLateral geniculate nucleusSuperior colliculusOptic tractRetinotopic map formationRetinal ganglion cell axonsBone morphogenetic proteinCentral brain targetsRetinocollicular map formationGanglion cell axonsMap formationWild-type miceStrains of miceAxon behaviorEarly eye formationAxon orderRetinal cell fateOptic chiasmRGC axonsBrain targetsGeniculate nucleusCell axonsPotential downstream effectorsAxon sortingMorphogenetic proteinsMiceRetinocollicular Synapse Maturation and Plasticity Are Regulated by Correlated Retinal Waves
Shah RD, Crair MC. Retinocollicular Synapse Maturation and Plasticity Are Regulated by Correlated Retinal Waves. Journal Of Neuroscience 2008, 28: 292-303. PMID: 18171946, PMCID: PMC6671137, DOI: 10.1523/jneurosci.4276-07.2008.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAlpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic AcidAnimalsAnimals, NewbornBehavior, AnimalDose-Response Relationship, RadiationElectric StimulationExcitatory Amino Acid AntagonistsIn Vitro TechniquesMiceMice, KnockoutN-MethylaspartateNeuronal PlasticityPatch-Clamp TechniquesQuinoxalinesReceptors, NicotinicRetinaSuperior ColliculiSynapsesSynaptic TransmissionVisual PathwaysConceptsFirst postnatal weekRetinal wavesPostnatal weekSynapse maturationAMPA/NMDA ratioRetinotopic map refinementSpontaneous retinal wavesNicotinic ACh receptorsSecond postnatal weekRetinocollicular synapsesSynapses decreasesPattern of activationNMDA ratioSynaptic strengtheningACh receptorsQuantal amplitudeRetinotopic map formationSuperior colliculusControl synapsesSynaptic changesCoincident activityPlasticity protocolsFirst weekBeta2 subunitWeeks