2019
Neurofunctional Differences Related to Methamphetamine and Sexual Cues in Men With Shorter and Longer Term Abstinence Methamphetamine Dependence
Chen S, Huang S, Yang C, Cai W, Chen H, Hao W, Liu T, Wang X, Worhunsky P, Potenza M. Neurofunctional Differences Related to Methamphetamine and Sexual Cues in Men With Shorter and Longer Term Abstinence Methamphetamine Dependence. The International Journal Of Neuropsychopharmacology 2019, 23: 135-145. PMID: 31995187, PMCID: PMC7171928, DOI: 10.1093/ijnp/pyz069.Peer-Reviewed Original ResearchConceptsHealthy comparison menFrontal cortex activationLong-term methamphetamine abstinenceSexual cuesNeutral cuesMethamphetamine cuesNeurofunctional differencesComparison menCortex activationLeft superior frontal cortexCue-related activationsNeutral visual cuesAnterior insula activationCue-reactivity taskAnterior insula responseVentromedial prefrontal cortexHealthy comparison participantsMethamphetamine abstinenceMethamphetamine dependenceFunctional magnetic resonanceWhole-brain analysisAbstinence groupSuperior frontal cortexInsula activationInsula response
2017
White-matter crossing-fiber microstructure in adolescents prenatally exposed to cocaine
Morie KP, Yip SW, Zhai ZW, Xu J, Hamilton KR, Sinha R, Mayes LC, Potenza MN. White-matter crossing-fiber microstructure in adolescents prenatally exposed to cocaine. Drug And Alcohol Dependence 2017, 174: 23-29. PMID: 28292689, PMCID: PMC5555052, DOI: 10.1016/j.drugalcdep.2017.01.011.Peer-Reviewed Original ResearchConceptsPrenatal cocaine exposureSuperior longitudinal fasciculusPCE adolescentsCrossing-fiber modelsGroup differencesWhole-brain investigationNon-exposed youthWhole-brain analysisSignificant group differencesAltered white matter developmentLeft superior longitudinal fasciculusRisk-taking behaviorNeurobiological underpinningsWhite matter developmentWhite matter microstructureSubstance useWhite matter differencesWhite matter regionsAdolescentsDiffusion-weighted imaging dataCocaine exposureLongitudinal cohortBilateral cingulumCorpus callosumROI analysis