2015
RNA ligation in neurons by RtcB inhibits axon regeneration
Kosmaczewski SG, Han SM, Han B, Meyer B, Baig HS, Athar W, Lin-Moore AT, Koelle MR, Hammarlund M. RNA ligation in neurons by RtcB inhibits axon regeneration. Proceedings Of The National Academy Of Sciences Of The United States Of America 2015, 112: 8451-8456. PMID: 26100902, PMCID: PMC4500288, DOI: 10.1073/pnas.1502948112.Peer-Reviewed Original Research
2012
Neural Regeneration in Caenorhabditis elegans
Bejjani R, Hammarlund M. Neural Regeneration in Caenorhabditis elegans. Annual Review Of Genetics 2012, 46: 499-513. PMID: 22974301, PMCID: PMC3700416, DOI: 10.1146/annurev-genet-110711-155550.Peer-Reviewed Original Research
2011
In vivo Laser Axotomy in C. elegans
Byrne AB, Edwards TJ, Hammarlund M. In vivo Laser Axotomy in C. elegans. Journal Of Visualized Experiments 2011, 2707. PMID: 21633331, PMCID: PMC3168200, DOI: 10.3791/2707.Peer-Reviewed Original Research
2009
Axon Regeneration Requires a Conserved MAP Kinase Pathway
Hammarlund M, Nix P, Hauth L, Jorgensen EM, Bastiani M. Axon Regeneration Requires a Conserved MAP Kinase Pathway. Science 2009, 323: 802-806. PMID: 19164707, PMCID: PMC2729122, DOI: 10.1126/science.1165527.Peer-Reviewed Original ResearchMeSH KeywordsAgingAnimalsAxonsAxotomyCaenorhabditis elegansCaenorhabditis elegans ProteinsGamma-Aminobutyric AcidGrowth ConesMAP Kinase Kinase 4MAP Kinase Kinase KinasesMAP Kinase Signaling SystemMitogen-Activated Protein KinasesModels, BiologicalMotor NeuronsMutationNerve RegenerationRNA InterferenceConceptsCell-intrinsic regeneration pathwaysKinase pathwayCaenorhabditis elegans motor neuronsMitogen-activated protein kinase pathwayMAP kinase cascadeMAP kinase pathwayProtein kinase pathwayGrowth cone migrationKinase cascadeRegeneration pathwayCone migrationLater stepsLack of activationDevelopment of therapiesMature neuronsPathwayAplastic statesMost neuronsRegenerationMotor neuronsAxon injuryAxon regenerationNeuron functionActivationNeurons