2020
Organization, Function, and Development of the Mouse Retinogeniculate Synapse
Liang L, Chen C. Organization, Function, and Development of the Mouse Retinogeniculate Synapse. Annual Review Of Vision Science 2020, 6: 261-285. PMID: 32936733, DOI: 10.1146/annurev-vision-121219-081753.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAxonsGeniculate BodiesHumansMiceRetinal Ganglion CellsSynaptic TransmissionThalamusVisual PathwaysConceptsRetinogeniculate synapseDistinct retinal ganglion cell typesRetinal ganglion cell typesGanglion cell typesImage-forming pathwayVisual thalamusThalamocortical neuronsVisual pathwayExperimental modelCircuit organizationThalamusSynapseMiceCell typesFunctional organizationRecent studiesPowerful experimental modelCurrent understandingVisual spaceVisual experiencePathwayNeuronsRGCsRetinal Inputs to the Thalamus Are Selectively Gated by Arousal
Liang L, Fratzl A, Reggiani JDS, El Mansour O, Chen C, Andermann ML. Retinal Inputs to the Thalamus Are Selectively Gated by Arousal. Current Biology 2020, 30: 3923-3934.e9. PMID: 32795442, PMCID: PMC7665906, DOI: 10.1016/j.cub.2020.07.065.Peer-Reviewed Original ResearchConceptsVisual thalamusVisual responsesMajority of boutonsTwo-photon calciumCentral visual processingArousal stateIntermediate spatial frequenciesEnhancement of responsesAxonal boutonsRetinal axonsRetinal inputDifferent pupil sizesVisual pathwayThalamusBoutonsMouse thalamusVisual processingMagnitude of responseVisual information channelsDistinct subsetsEarly stagesPupil sizeNeural activityDifferential modulationBehavioral states
2018
A Fine-Scale Functional Logic to Convergence from Retina to Thalamus
Liang L, Fratzl A, Goldey G, Ramesh RN, Sugden AU, Morgan JL, Chen C, Andermann ML. A Fine-Scale Functional Logic to Convergence from Retina to Thalamus. Cell 2018, 173: 1343-1355.e24. PMID: 29856953, PMCID: PMC6003778, DOI: 10.1016/j.cell.2018.04.041.Peer-Reviewed Original ResearchConceptsAxonal boutonsRetinal ganglion cellsTwo-photon calciumImage-forming visionClusters of boutonsVisual thalamusGanglion cellsRetinal axonsBouton clustersThalamusMouse thalamusIndividual axonsDifferent axonsFeature selectivityBoutonsFine-scale organizationAxonsDendritic domainsUltrastructural analysisRetina