2011
MicroRNA181a plays a key role in hair cell regeneration in the avian auditory epithelium
Frucht CS, Santos-Sacchi J, Navaratnam DS. MicroRNA181a plays a key role in hair cell regeneration in the avian auditory epithelium. Neuroscience Letters 2011, 493: 44-48. PMID: 21316421, PMCID: PMC3065390, DOI: 10.1016/j.neulet.2011.02.017.Peer-Reviewed Original ResearchConceptsHair cell regenerationHair cell deathAuditory epitheliumChicken auditory epitheliumCell deathNon-mammalian vertebratesAvian auditory epitheliumCell regenerationHair cellsBasilar papillaNew hair cellsChicken basilar papillaAvian counterpartsOtotoxic injuryCaspase-3MiRNACellsMiR181aKey roleExplantsProliferationRegenerationBrdU-positive cellsVertebratesMammals
2010
Gene Expression Analysis of Forskolin Treated Basilar Papillae Identifies MicroRNA181a as a Mediator of Proliferation
Frucht CS, Uduman M, Duke JL, Kleinstein SH, Santos-Sacchi J, Navaratnam DS. Gene Expression Analysis of Forskolin Treated Basilar Papillae Identifies MicroRNA181a as a Mediator of Proliferation. PLOS ONE 2010, 5: e11502. PMID: 20634979, PMCID: PMC2901389, DOI: 10.1371/journal.pone.0011502.Peer-Reviewed Original ResearchConceptsNew hair cellsAuditory epitheliumChicken auditory epitheliumHair cellsInner ear developmentHair cell regenerationGene expression analysisAuditory hair cellsEar developmentExpression analysisMyosin VIEnrichment analysisCycle controlGene expressionMolecular eventsSingle microRNAMediator of proliferationRelevant pathwaysFunctional experimentsPost-hatch chicksRegenerating tissueMammalsGenesBrdU incorporationCell regeneration