1996
Effects of Salicylate and Lanthanides on Outer Hair Cell Motility and Associated Gating Charge
Kakehata S, Santos-Sacchi J. Effects of Salicylate and Lanthanides on Outer Hair Cell Motility and Associated Gating Charge. Journal Of Neuroscience 1996, 16: 4881-4889. PMID: 8756420, PMCID: PMC6579298, DOI: 10.1523/jneurosci.16-16-04881.1996.Peer-Reviewed Original ResearchConceptsOuter hair cellsEffects of salicylateConcentration-response curvesGuinea pig outer hair cellsOHC motilityAuditory frequency selectivityForm of salicylateHalf-maximal concentrationReversible tinnitusHearing lossDepolarized levelsHair cell motilityComparable groupsHair cellsOuter Hair Cell MotilityInner aspectOuter aspectSubsurface cisternaeTrypsin treatmentMotilityPressure changesHill coefficientSalicylatePresent experimentsVoltage-induced movement
1995
Membrane tension directly shifts voltage dependence of outer hair cell motility and associated gating charge
Kakehata S, Santos-Sacchi J. Membrane tension directly shifts voltage dependence of outer hair cell motility and associated gating charge. Biophysical Journal 1995, 68: 2190-2197. PMID: 7612863, PMCID: PMC1282124, DOI: 10.1016/s0006-3495(95)80401-7.Peer-Reviewed Original ResearchConceptsIntracellular turgor pressureCortical cytoskeletal networkIntracellular pressureOuter hair cellsCytoskeletal networkCell motilityMammalian basilar membraneCytoskeletal elementsTurgor pressureOHC motorMembrane tensionCell collapseMechanical vibrationNonlinear capacitanceVoltage-dependent capacitanceHair cell motilityGating chargeHair cellsCell configurationCapacitanceMembrane stressOuter hair cell motilityWhole-cell voltage-clamp configurationMotility