2006
Control of Mammalian Cochlear Amplification by Chloride Anions
Santos-Sacchi J, Song L, Zheng J, Nuttall AL. Control of Mammalian Cochlear Amplification by Chloride Anions. Journal Of Neuroscience 2006, 26: 3992-3998. PMID: 16611815, PMCID: PMC6673883, DOI: 10.1523/jneurosci.4548-05.2006.Peer-Reviewed Original Research
2001
Furosemide alters nonlinear capacitance in isolated outer hair cells
Santos-Sacchi J, Wu M, Kakehata S. Furosemide alters nonlinear capacitance in isolated outer hair cells. Hearing Research 2001, 159: 69-73. PMID: 11520635, DOI: 10.1016/s0378-5955(01)00321-5.Peer-Reviewed Original ResearchConceptsOuter hair cellsWhole-cell patch-clamp techniqueHair cellsNormal cochlear functionIsolated outer hair cellsPatch-clamp techniqueOrgan of CortiLoop diureticsSensory dysfunctionHearing resultsCochlear functionEndolymphatic potentialFurosemideDirect effectHill coefficientPositive levelCellsDiureticsDysfunctionPresent results
1987
Electrical coupling differs in the in vitro and in vivo organ of Corti
Santos-Sacchi J. Electrical coupling differs in the in vitro and in vivo organ of Corti. Hearing Research 1987, 25: 227-232. PMID: 3558131, DOI: 10.1016/0378-5955(87)90094-3.Peer-Reviewed Original ResearchConceptsOrgan of CortiBony cochleaVivo preparationInner earLateral wallGuinea pig organAnesthetized animalsPig organsStria vascularisEndolymphatic potentialCortiReissner's membraneMedium 199Perfusion chamberCochleaVivo experimentsApical sideOrgansKCl electrodesM KCl electrodesElectrical couplingUnique microenvironmentCellsEarThird turn