2020
Connectomic analysis reveals an interneuron with an integral role in the retinal circuit for night vision
Park SJ, Lieberman EE, Ke JB, Rho N, Ghorbani P, Rahmani P, Jun NY, Lee HL, Kim IJ, Briggman KL, Demb JB, Singer JH. Connectomic analysis reveals an interneuron with an integral role in the retinal circuit for night vision. ELife 2020, 9: e56077. PMID: 32412412, PMCID: PMC7228767, DOI: 10.7554/elife.56077.Peer-Reviewed Original ResearchConceptsAII amacrine cellsProjection neuronsSingle interneuron typeConnectomic analysisBipolar cell pathwaysNovel neural circuitGABAergic cellsAmacrine cellsCentral neuronsGanglion cellsSynaptic layersRetinal circuitsInterneuron typesSurround inhibitionMouse retinaNight visionON responseExcitatory centerOptogenetic analysesNeural circuitsInhibitory surroundCell pathwaysRod photoreceptorsReceptive fieldsRb pathway
2010
Information Processing: Contrast Sensitivity
Manookin M, Demb J. Information Processing: Contrast Sensitivity. 2010, 344-348. DOI: 10.1016/b978-0-12-374203-2.00199-8.Chapters
2008
Functional circuitry of visual adaptation in the retina
Demb JB. Functional circuitry of visual adaptation in the retina. The Journal Of Physiology 2008, 586: 4377-4384. PMID: 18617564, PMCID: PMC2614018, DOI: 10.1113/jphysiol.2008.156638.Peer-Reviewed Original ResearchConceptsPresynaptic bipolar cellsGanglion cellsReceptive field centerBipolar cellsGanglion cell receptive field centersPeripheral receptive fieldsBipolar cell inputsContrast adaptationRetinal ganglion cellsBipolar terminalsGlutamate releaseAmacrine cellsSynaptic outputMammalian retinaContrast stimulationFunctional circuitryCellular mechanismsSpike generationCell inputHyperpolarizationReceptive fieldsRetinaResponse saturationField centerCells
2005
Do We Know What the Early Visual System Does?
Carandini M, Demb JB, Mante V, Tolhurst DJ, Dan Y, Olshausen BA, Gallant JL, Rust NC. Do We Know What the Early Visual System Does? Journal Of Neuroscience 2005, 25: 10577-10597. PMID: 16291931, PMCID: PMC6725861, DOI: 10.1523/jneurosci.3726-05.2005.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2001
Bipolar Cells Contribute to Nonlinear Spatial Summation in the Brisk-Transient (Y) Ganglion Cell in Mammalian Retina
Demb J, Zaghloul K, Haarsma L, Sterling P. Bipolar Cells Contribute to Nonlinear Spatial Summation in the Brisk-Transient (Y) Ganglion Cell in Mammalian Retina. Journal Of Neuroscience 2001, 21: 7447-7454. PMID: 11567034, PMCID: PMC6762908, DOI: 10.1523/jneurosci.21-19-07447.2001.Peer-Reviewed Original ResearchConceptsBipolar cellsGanglion cellsBrisk-transient ganglion cellsReceptive fieldsExcitatory postsynaptic potentialsGuinea pig retinaNonlinear spatial summationNonlinear receptive fieldsAmacrine cellsPostsynaptic potentialsPig retinaExcitatory mechanismsMammalian retinaY cellsLinear receptive fieldsSpatial summationBipolar inputRetinaCellsPeripheral componentsCentral componentAcetylcholineTetrodotoxinGABA
1999
Functional Circuitry of the Retinal Ganglion Cell's Nonlinear Receptive Field
Demb J, Haarsma L, Freed M, Sterling P. Functional Circuitry of the Retinal Ganglion Cell's Nonlinear Receptive Field. Journal Of Neuroscience 1999, 19: 9756-9767. PMID: 10559385, PMCID: PMC6782950, DOI: 10.1523/jneurosci.19-22-09756.1999.Peer-Reviewed Original ResearchConceptsGanglion cellsDendritic fieldsContrast-reversing gratingsNonlinear receptive fieldsOFF ganglion cellsReceptive fieldsCell dendritic fieldsRetinal ganglion cellsGuinea pig retinaBipolar cell responsesReceptive field mechanismsSurround responsesBipolar cellsPig retinaCell responsesFunctional circuitryL-APVisual stimuliMembrane potentialSingle classCellsResponseInterneuronsTetrodotoxinRetina