2012
Reward-Related Dorsal Striatal Activity Differences between Former and Current Cocaine Dependent Individuals during an Interactive Competitive Game
Hyatt CJ, Assaf M, Muska CE, Rosen RI, Thomas AD, Johnson MR, Hylton JL, Andrews MM, Reynolds BA, Krystal JH, Potenza MN, Pearlson GD. Reward-Related Dorsal Striatal Activity Differences between Former and Current Cocaine Dependent Individuals during an Interactive Competitive Game. PLOS ONE 2012, 7: e34917. PMID: 22606228, PMCID: PMC3351439, DOI: 10.1371/journal.pone.0034917.Peer-Reviewed Original Research
2002
Sensory gating and psychosis vulnerability in cocaine-dependent individuals: preliminary data
Boutros NN, Gelernter J, Gooding DC, Cubells J, Young A, Krystal JH, Kosten T. Sensory gating and psychosis vulnerability in cocaine-dependent individuals: preliminary data. Biological Psychiatry 2002, 51: 683-686. PMID: 11955469, DOI: 10.1016/s0006-3223(01)01237-9.Peer-Reviewed Original Research
2001
Quantitative Morphology of the Caudate and Putamen in Patients With Cocaine Dependence
Jacobsen LK, Giedd JN, Gottschalk C, Kosten TR, Krystal JH. Quantitative Morphology of the Caudate and Putamen in Patients With Cocaine Dependence. American Journal Of Psychiatry 2001, 158: 486-489. PMID: 11229995, DOI: 10.1176/appi.ajp.158.3.486.Peer-Reviewed Original ResearchMeSH KeywordsAdultBrainCaudate NucleusCocaine-Related DisordersCorpus StriatumDopamineFemaleHumansHypertrophyMagnetic Resonance ImagingMaleMiddle AgedPutamenConceptsCocaine dependenceDopaminergic functionStriatal dopaminergic depletionTypical neuroleptic treatmentTotal brain volumeChronic cocaine dependenceCocaine-dependent subjectsChronic cocaine useStriatal hypertrophyExtrapyramidal symptomsNeuroleptic treatmentDopaminergic depletionHealthy subjectsBrain volumePutamen volumeCocaine useStriatal structuresCaudatePatientsPutamenHypertrophyMagnetic resonanceDeficitsQuantitative morphologySubjectsElevated motor threshold in drug-free, cocaine-dependent patients assessed with transcranial magnetic stimulation
Boutros N, Lisanby S, Tokuno H, Torello M, Campbell D, Berman R, Malison R, Krystal J, Kosten T. Elevated motor threshold in drug-free, cocaine-dependent patients assessed with transcranial magnetic stimulation. Biological Psychiatry 2001, 49: 369-373. PMID: 11239908, DOI: 10.1016/s0006-3223(00)00948-3.Peer-Reviewed Original ResearchMeSH KeywordsAdultChronic DiseaseCocaine-Related DisordersElectroencephalographyFemaleHumansMaleMiddle AgedMotor CortexPilot ProjectsSensory ThresholdsTranscranial Magnetic StimulationConceptsTranscranial magnetic stimulationCortical excitabilityCocaine-dependent subjectsMotor thresholdControl subjectsMagnetic stimulationSingle-pulse transcranial magnetic stimulationExcitatory/inhibitory balancePulse transcranial magnetic stimulationChronic cocaine abuseMotor cortical regionsChronic cocaine abusersNormal control subjectsNumber of neurotransmittersAlters cortical excitabilityCocaine-dependent patientsCortical inhibitoryCerebral cortexInhibitory balanceAwake subjectsChronic cocaineCocaine intoxicationCocaine abusePsychiatric populationsCortical regions
2000
Cocaine use and the mid-latency auditory evoked responses
Boutros N, Campbell D, Petrakis I, Krystal J, Caporale M, Kosten T. Cocaine use and the mid-latency auditory evoked responses. Psychiatry Research 2000, 96: 117-126. PMID: 11063784, DOI: 10.1016/s0165-1781(00)00207-9.Peer-Reviewed Original ResearchConceptsCocaine-dependent subjectsInter-stimulus intervalMid-latency auditoryAge-matched healthy control subjectsCocaine useHealthy control subjectsDifferent inter-stimulus intervalsChronic cocaine useLong inter-stimulus intervalsPaired-click paradigmControl subjectsP50 componentN100 componentSignificant decreaseSubjectsAuditoryResponse paradigm