2019
Reduced Salience and Enhanced Central Executive Connectivity Following PTSD Treatment
Abdallah CG, Averill CL, Ramage AE, Averill LA, Alkin E, Nemati S, Krystal JH, Roache JD, Resick P, Young-McCaughan S, Peterson AL, Fox P. Reduced Salience and Enhanced Central Executive Connectivity Following PTSD Treatment. Chronic Stress 2019, 3: 2470547019838971. PMID: 31008419, PMCID: PMC6469713, DOI: 10.1177/2470547019838971.Peer-Reviewed Original ResearchPosttraumatic stress disorderCognitive processing therapyCentral executive networkSymptom provocationPTSD treatmentSecondary analysisGroup cognitive processing therapyPTSD participantsGlobal brain connectivityEffective PTSD treatmentExecutive networkFunctional magnetic resonance imagingMagnetic resonance imagingEffect of treatmentUnknown neurobiological mechanismsUS Army soldiersTreatment periodWeek 8Higher pretreatmentMRI scansPrimary analysisResonance imagingSalience networkStress disorderBrain connectivity
2016
Hostility and telomere shortening among U.S. military veterans: Results from the National Health and Resilience in Veterans Study
Watkins LE, Harpaz-Rotem I, Sippel LM, Krystal JH, Southwick SM, Pietrzak RH. Hostility and telomere shortening among U.S. military veterans: Results from the National Health and Resilience in Veterans Study. Psychoneuroendocrinology 2016, 74: 251-257. PMID: 27689898, DOI: 10.1016/j.psyneuen.2016.09.006.Peer-Reviewed Original ResearchConceptsU.S. military veteransClinical variablesNational HealthTelomere lengthMilitary veteransMultivariable binary logistic regression analysisVeterans StudyAccelerated cellular agingBinary logistic regression analysisLogistic regression analysisU.S. veteran populationNon-veteran populationsAge-related disordersPolymerase chain reaction methodChronic disordersRisk factorsChain reaction methodQuantitative polymerase chain reaction methodVeteran populationU.S. veteransSecondary analysisTreatment effortsVeteransRegression analysisBiological age
2007
Family History of Alcoholism Influences Naltrexone-Induced Reduction in Alcohol Drinking
Krishnan-Sarin S, Krystal JH, Shi J, Pittman B, O’Malley S. Family History of Alcoholism Influences Naltrexone-Induced Reduction in Alcohol Drinking. Biological Psychiatry 2007, 62: 694-697. PMID: 17336941, DOI: 10.1016/j.biopsych.2006.11.018.Peer-Reviewed Original ResearchConceptsAlcohol drinkingFamily historyDrinking periodDose of naltrexoneSignificant clinical predictorsNaltrexone therapyClinical predictorsNaltrexone dosePriming doseMale drinkersNaltrexoneAlcohol-dependent participantsSecondary analysisDoseAlcoholic drinksDrinkingAlcoholismDrinkersDrinksDaysTotal numberParticipantsTherapy