NO Association Between an Allele at the D2 Dopamine Receptor Gene (DRD2) and Alcoholism
Gelernter J, O'Malley S, Risch N, Kranzler HR, Krystal J, Merikangas K, Kennedy JL, Kidd KK. NO Association Between an Allele at the D2 Dopamine Receptor Gene (DRD2) and Alcoholism. JAMA 1991, 266: 1801-1807. PMID: 1832467, DOI: 10.1001/jama.1991.03470130081033.Peer-Reviewed Original ResearchConceptsControl groupA1 allelePopulation control groupPhysical withdrawal symptomsRandom population controlsSignificant differencesAge of onsetRecent alcohol consumptionAllele frequenciesD2 dopamine receptor geneAntisocial personality disorderWithdrawal symptomsFamily historyAlcoholic subjectsDirect structured interviewsGroup overallAllelic associationDopamine receptor geneAlcohol consumptionAlcohol dependenceControl populationPositive allelic associationAlcoholismPersonality disorderWhite individuals