2021
Polygenic risk for traumatic loss-related PTSD in US military veterans: Protective effect of secure attachment style
Asch RH, Esterlis I, Wendt FR, Kachadourian L, Southwick SM, Gelernter J, Polimanti R, Pietrzak RH. Polygenic risk for traumatic loss-related PTSD in US military veterans: Protective effect of secure attachment style. The World Journal Of Biological Psychiatry 2021, 22: 792-799. PMID: 33821766, PMCID: PMC8925016, DOI: 10.1080/15622975.2021.1907721.Peer-Reviewed Original ResearchConceptsAttachment styleSecure attachment styleRe-experiencing symptomsPolygenic riskAttachment securityPsychological treatmentTraumatic eventsPositive screenPTSDStyle interactionPolygenic risk scoresUS military veteransMilitary veteransNeuroplasticity processesGenetic liabilityStyleSignificant predictorsVeteransUS veteransAssociationPredictorsScreenScoresSeverityRelationship
2018
Multivariate Pattern Analysis of Genotype–Phenotype Relationships in Schizophrenia
Zheutlin AB, Chekroud AM, Polimanti R, Gelernter J, Sabb FW, Bilder RM, Freimer N, London ED, Hultman CM, Cannon TD. Multivariate Pattern Analysis of Genotype–Phenotype Relationships in Schizophrenia. Schizophrenia Bulletin 2018, 44: 1045-1052. PMID: 29534239, PMCID: PMC6101611, DOI: 10.1093/schbul/sby005.Peer-Reviewed Original ResearchConceptsMultivariate pattern analysisIndependent samplesVisual memoryCognitive endophenotypesPredictive strengthSchizophreniaMemoryIndividual variationPattern analysisSingle predictorCertain domainsDiscovery samplePsychiatric patientsPolygenic risk scoresPredictive powerScoresEndophenotypesPotential relationshipRelationshipRandom forestGenetic risk variantsLimited setPredictorsComprehensive setSamples