2019
FUNCTIONAL CODING VARIANT IN OPRM1 GENE ASSOCIATED WITH OPIOID USE DISORDER: EVIDENCE FROM GWAS ON LARGE COHORTS
Zhou H, Rentsch C, Cheng Z, Kember R, Nunex Y, Tate J, Dao C, Polimanti R, Justice A, Kranzler H, Gelernter J. FUNCTIONAL CODING VARIANT IN OPRM1 GENE ASSOCIATED WITH OPIOID USE DISORDER: EVIDENCE FROM GWAS ON LARGE COHORTS. European Neuropsychopharmacology 2019, 29: s34-s35. DOI: 10.1016/j.euroneuro.2019.07.070.Peer-Reviewed Original Research
2016
Genome-wide Association Study of Cannabis Dependence Severity, Novel Risk Variants, and Shared Genetic Risks
Sherva R, Wang Q, Kranzler H, Zhao H, Koesterer R, Herman A, Farrer LA, Gelernter J. Genome-wide Association Study of Cannabis Dependence Severity, Novel Risk Variants, and Shared Genetic Risks. JAMA Psychiatry 2016, 73: 472. PMID: 27028160, PMCID: PMC4974817, DOI: 10.1001/jamapsychiatry.2016.0036.Peer-Reviewed Original ResearchConceptsCannabis dependenceNeuronal calcium homeostasisGenetic factorsMajor depressive disorderSushi multiple domains-1 (CSMD1) geneSubstance abuse treatment centersSpecific genetic risk factorsGenetic risk factorsShared genetic riskPotential genetic factorsCentral nervous system developmentCriterion countsCannabis dependence severityDomain 1 geneCAD riskMean ageRisk factorsDepressive disorderNervous system developmentMajor depressionLarge cohortMAIN OUTCOMEGenome-wide association studiesTreatment centersCalcium homeostasis