2022
Spatiotemporally heterogeneous coordination of cholinergic and neocortical activity
Lohani S, Moberly A, Benisty H, Landa B, Jing M, Li Y, Higley M, Cardin J. Spatiotemporally heterogeneous coordination of cholinergic and neocortical activity. Nature Neuroscience 2022, 25: 1706-1713. PMID: 36443609, PMCID: PMC10661869, DOI: 10.1038/s41593-022-01202-6.Peer-Reviewed Original ResearchConceptsCortical network activityBehavioral statesCholinergic modulationAnimal's behavioral stateCholinergic signalingAwake miceCortical functionFunctional reorganizationNeuromodulatory influencesDifferent motor behaviorsNeocortical activityAcetylcholineMotor behaviorCortical networksRecent evidenceBrain activityFunctional segregationNeocortexMesoscopic imagingHeterogeneous signalsNetwork activityBehavioral markersBehavioral variablesCircuit dynamicsCholinergic
2015
Arousal and Locomotion Make Distinct Contributions to Cortical Activity Patterns and Visual Encoding
Vinck M, Batista-Brito R, Knoblich U, Cardin JA. Arousal and Locomotion Make Distinct Contributions to Cortical Activity Patterns and Visual Encoding. Neuron 2015, 86: 740-754. PMID: 25892300, PMCID: PMC4425590, DOI: 10.1016/j.neuron.2015.03.028.Peer-Reviewed Original ResearchConceptsSensory-evoked cortical activityCortical activity patternsLocomotion effectsMouse V1Spontaneous firingLocal field potentialsCortical circuitsCortical activityRunning wheelArea V1Visual responsesPatterns of activityPupil diameterPopulation activityField potentialsMotor feedbackArousalV1Activity patternsArousal levelTemporal patterningComplementary roleMiceActivity