1998
Peripheral Axotomy Induces Long-Term c-Jun Amino-Terminal Kinase-1 Activation and Activator Protein-1 Binding Activity by c-Jun and junD in Adult Rat Dorsal Root Ganglia In Vivo
Kenney A, Kocsis J. Peripheral Axotomy Induces Long-Term c-Jun Amino-Terminal Kinase-1 Activation and Activator Protein-1 Binding Activity by c-Jun and junD in Adult Rat Dorsal Root Ganglia In Vivo. Journal Of Neuroscience 1998, 18: 1318-1328. PMID: 9454841, PMCID: PMC2605350, DOI: 10.1523/jneurosci.18-04-01318.1998.Peer-Reviewed Original ResearchConceptsC-Jun proteinC-JunC-Jun amino-terminal kinase 1Nerve injuryAxonal regenerationAmino-terminal phosphorylationLumbar dorsal root ganglion neuronsActivator protein-1 bindingEarly post-injury periodJun kinase activationAdult rat dorsal root gangliaDorsal root ganglion neuronsRat dorsal root gangliaKinase 1 activationC-Jun phosphorylationSciatic nerve injuryActivator protein-1 binding activityPost-injury periodSciatic nerve transectionAdult rat DRGDorsal root gangliaLong-term upregulationPeripheral axonal regenerationAP-1 bindingProtein-1 bindingMechanisms of enhancement of neurite regeneration in vitro following a conditioning sciatic nerve lesion
Lankford K, Waxman S, Kocsis J. Mechanisms of enhancement of neurite regeneration in vitro following a conditioning sciatic nerve lesion. The Journal Of Comparative Neurology 1998, 391: 11-29. PMID: 9527536, PMCID: PMC2605358, DOI: 10.1002/(sici)1096-9861(19980202)391:1<11::aid-cne2>3.0.co;2-u.Peer-Reviewed Original ResearchConceptsDorsal root gangliaConditioning lesionNerve injuryNerve regenerationAffected dorsal root ganglionControl dorsal root gangliaDenervated peripheral nervePrior nerve injurySciatic nerve lesionCultured DRG neuronsSciatic nerve transectionPeripheral target tissuesPeripheral nerve stumpRapid nerve regenerationAbility of neuronsSecond axotomyNerve lesionsDRG neuronsNerve transectionNerve stumpRoot gangliaControl neuronsPeripheral nervesNerve tractsAdult rats
1997
Timing of c-jun protein induction in lumbar dorsal root ganglia after sciatic nerve transection varies with lesion distance
Kenney A, Kocsis J. Timing of c-jun protein induction in lumbar dorsal root ganglia after sciatic nerve transection varies with lesion distance. Brain Research 1997, 751: 90-95. PMID: 9098571, DOI: 10.1016/s0006-8993(96)01402-3.Peer-Reviewed Original ResearchConceptsSciatic nerve transectionNerve transectionDorsal root gangliaNerve injuryRoot gangliaLumbar dorsal root ganglion neuronsL5 dorsal root gangliaLumbar dorsal root gangliaDorsal root ganglion neuronsSciatic nerve injurySciatic nerve crushC-Jun proteinProtein inductionC-Jun responseNerve crushGanglion neuronsImmunohistochemical studyLesion distanceTransectionInduces upregulationEarly increaseC-jun mRNAEarly inductionChemiluminescent immunoblottingGanglia