Featured Publications
Reinforcement learning detuned in addiction: integrative and translational approaches
Groman SM, Thompson SL, Lee D, Taylor JR. Reinforcement learning detuned in addiction: integrative and translational approaches. Trends In Neurosciences 2021, 45: 96-105. PMID: 34920884, PMCID: PMC8770604, DOI: 10.1016/j.tins.2021.11.007.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsDecision-making deficitsPathophysiology of addictionDecision-making strategiesBiobehavioral mechanismsAddictionReinforcement learningDecision-making processDrug useTranslational approachComputational componentsDeficitsLearningDifferent componentsBiological mechanismsOutcomesFindingsRecent studiesBehaviorStudy
2013
Chapter 13 The Translational Potential of Memory Reconsolidation
Corlett P, Taylor J. Chapter 13 The Translational Potential of Memory Reconsolidation. 2013, 273-292. DOI: 10.1016/b978-0-12-386892-3.00013-5.Peer-Reviewed Original ResearchPost-traumatic stress disorderMemory labileMemory reconsolidationMemory processingLabile stateStress disorderMemory erasureDrug addictionPast experienceReconsolidationSerious mental illnessCurrent processingMemoryMental illnessProcessingAddictionEthical implicationsChapter 13PsychosisDisordersImplicationsIllnessExperience
2008
Targeting extinction and reconsolidation mechanisms to combat the impact of drug cues on addiction
Taylor JR, Olausson P, Quinn JJ, Torregrossa MM. Targeting extinction and reconsolidation mechanisms to combat the impact of drug cues on addiction. Neuropharmacology 2008, 56: 186-195. PMID: 18708077, PMCID: PMC2635342, DOI: 10.1016/j.neuropharm.2008.07.027.Peer-Reviewed Original ResearchConceptsCue-drug memoriesCue-drug associationsCue exposure therapyMemory reconsolidation processesDisruption of reconsolidationCue-induced relapseDrug-associated cuesInhibitory memoryReconsolidation mechanismsDrug cuesMemory retrievalReconsolidation processMemory processesReconsolidationCompulsive disorderRelapse behaviorMemoryMemory erasureBrief time periodDrug addictionDistinct processesCuesAddictionExtinctionCraving