2013
PINK1 protects against cell death induced by mitochondrial depolarization, by phosphorylating Bcl-xL and impairing its pro-apoptotic cleavage
Arena G, Gelmetti V, Torosantucci L, Vignone D, Lamorte G, De Rosa P, Cilia E, Jonas EA, Valente EM. PINK1 protects against cell death induced by mitochondrial depolarization, by phosphorylating Bcl-xL and impairing its pro-apoptotic cleavage. Cell Death & Differentiation 2013, 20: 920-930. PMID: 23519076, PMCID: PMC3679455, DOI: 10.1038/cdd.2013.19.Peer-Reviewed Original ResearchConceptsBcl-xLMitochondrial depolarizationCell deathPro-autophagic protein Beclin-1Autosomal recessive Parkinson's diseaseBeclin-1Recessive Parkinson's diseaseAnti-apoptotic proteinsXL interactionMitochondrial kinaseProtein Beclin 1Mitochondrial traffickingMitochondrial homeostasisMitophagy pathwayBcl-xL.PINK1Functional linkCell survivalPathogenesis of PDNovel mechanismPINK1 genePathwayCleavageMitophagyParkinson's disease
1996
Regulation of potassium channels by protein kinases
Jonas E, Kaczmarek L. Regulation of potassium channels by protein kinases. Current Opinion In Neurobiology 1996, 6: 318-323. PMID: 8794088, DOI: 10.1016/s0959-4388(96)80114-0.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsAnimalsCell MembraneEnzyme ActivationHumansKineticsPhosphorylationPotassium ChannelsProtein KinasesSerineThreonineTyrosine