2004
Multiple Large Inputs to Principal Cells in the Mouse Medial Nucleus of the Trapezoid Body
Bergsman JB, De Camilli P, McCormick DA. Multiple Large Inputs to Principal Cells in the Mouse Medial Nucleus of the Trapezoid Body. Journal Of Neurophysiology 2004, 92: 545-552. PMID: 15212444, DOI: 10.1152/jn.00927.2003.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAuditory PathwaysBrain StemElectric StimulationExcitatory Amino Acid AntagonistsExcitatory Postsynaptic PotentialsMiceMice, Inbred BALB CMice, Inbred C57BLConceptsPrincipal cellsTrapezoid bodyElectrophysiological criteriaMedial nucleusNerve terminalsMammalian auditory brain stemExcitatory postsynaptic current amplitudeCalyceal nerve terminalsMouse medial nucleusAuditory brain stemPostsynaptic current amplitudeStrong excitatory inputGiant nerve terminalCalyx of HeldPrincipal neuronsBrain stemExcitatory inputsSynaptic transmissionCentral synapseAnatomical studySynapseSound localizationTransmitter typeCellsCurrent amplitude
2001
Synaptojanin 1 Contributes to Maintaining the Stability of GABAergic Transmission in Primary Cultures of Cortical Neurons
Lüthi A, Di Paolo G, Cremona O, Daniell L, De Camilli P, McCormick D. Synaptojanin 1 Contributes to Maintaining the Stability of GABAergic Transmission in Primary Cultures of Cortical Neurons. Journal Of Neuroscience 2001, 21: 9101-9111. PMID: 11717343, PMCID: PMC6763888, DOI: 10.1523/jneurosci.21-23-09101.2001.Peer-Reviewed Original ResearchMeSH KeywordsAction PotentialsAnimalsAnimals, NewbornCells, CulturedCerebral CortexElectric StimulationExcitatory Amino Acid AntagonistsExcitatory Postsynaptic PotentialsGABA AntagonistsGamma-Aminobutyric AcidMiceNerve Tissue ProteinsNeural InhibitionNeuronsPatch-Clamp TechniquesPhosphatidylinositolsPhosphoric Monoester HydrolasesSodium Channel BlockersSynapsesSynaptic TransmissionSynaptic VesiclesConceptsPaired-pulse depressionHalf-maximal depressionSteady-state depressionSynaptic depressionWhole-cell patch-clamp recordingsSlow depressionInhibitory synaptic responsesPaired-pulse protocolPrimary cortical culturesHigh-frequency stimulationPatch-clamp recordingsBi-exponential time courseUnitary IPSCsGABA releaseGABAergic transmissionCortical culturesPostsynaptic responsesCortical neuronsInhibitory synapsesSynaptic responsesSynaptojanin 1Presynaptic stimulationInhibitory neuronsRelease probabilityStimulation frequency
1995
Electrophysiological and pharmacological properties of interneurons in the cat dorsal lateral geniculate nucleus
Pape H, McCormick D. Electrophysiological and pharmacological properties of interneurons in the cat dorsal lateral geniculate nucleus. Neuroscience 1995, 68: 1105-1125. PMID: 8544986, DOI: 10.1016/0306-4522(95)00205-w.Peer-Reviewed Original ResearchMeSH KeywordsAction PotentialsAnimalsCatsElectric StimulationElectrophysiologyExcitatory Amino Acid AgonistsExcitatory Amino Acid AntagonistsGABA-A Receptor AgonistsGABA-A Receptor AntagonistsGABA-B Receptor AgonistsGABA-B Receptor AntagonistsGamma-Aminobutyric AcidGeniculate BodiesIn Vitro TechniquesInterneuronsPatch-Clamp TechniquesThalamusConceptsDorsal lateral geniculate nucleusCat dorsal lateral geniculate nucleusLateral geniculate nucleusAction potentialsGeniculate nucleusGABAB receptor agonist baclofenGABAA receptor agonist muscimolSpontaneous action potential activityPharmacological propertiesStrong spike frequency adaptationSmall slow depolarizationSubpopulation of interneuronsReceptor agonist baclofenSpontaneous spike activityAction potential dischargeDorsal lateral geniculateReceptor agonist muscimolApplication of serotoninAction potential activityApplication of acetylcholineChloride equilibrium potentialHigh-frequency trainsSpike frequency adaptationUnique electrophysiological characteristicsAgonist baclofen