2004
Histamine modulates thalamocortical activity by activating a chloride conductance in ferret perigeniculate neurons
Lee K, Broberger C, Kim U, McCormick D. Histamine modulates thalamocortical activity by activating a chloride conductance in ferret perigeniculate neurons. Proceedings Of The National Academy Of Sciences Of The United States Of America 2004, 101: 6716-6721. PMID: 15096604, PMCID: PMC404111, DOI: 10.1073/pnas.0400817101.Peer-Reviewed Original ResearchConceptsApplication of histamineGamma-aminobutyric acidPerigeniculate nucleusGABAergic neuronsSingle spike activityMammalian central nervous systemCentral nervous systemHistaminergic actionPerigeniculate neuronsHistaminergic fibersHistaminergic systemHistaminergic receptorsTuberomammillary nucleusIontophoretic applicationPostsynaptic factorsThalamocortical activityInhibitory responsesNeuronal activityThalamic oscillationsNervous systemHistamineMembrane hyperpolarizationSpindle wavesIonotropic receptorsReversal potential
1992
Chapter 10 Determination of State-Dependent Processing in Thalamus by Single Neuron Properties and Neuromodulators
MCCORMICK D, STROWBRIDGE B, HUGUENARD J. Chapter 10 Determination of State-Dependent Processing in Thalamus by Single Neuron Properties and Neuromodulators. 1992, 259-290. DOI: 10.1016/b978-0-12-484815-3.50017-7.Peer-Reviewed Original ResearchState-dependent processingRelay neuronsSingle neuron propertiesHyperpolarization-activated cation currentNeuron propertiesThalamic relay neuronsAction potential generationThalamic neuronsCentral neuronsRhythmic burstsNervous systemCation currentSynaptic connectionsPacemaker currentThalamusNeuronsMotor informationPotential generationNeuromodulatorsFunctional consequences
1986
Acetylcholine induces burst firing in thalamic reticular neurones by activating a potassium conductance
McCormick D, Prince D. Acetylcholine induces burst firing in thalamic reticular neurones by activating a potassium conductance. Nature 1986, 319: 402-405. PMID: 2418361, DOI: 10.1038/319402a0.Peer-Reviewed Original ResearchConceptsNeuronal activityCholinergic inhibitory mechanismSingle spike activityRole of acetylcholineApplication of acetylcholineCentral nervous systemIntrinsic membrane propertiesAcetylcholine inducesM2 subclassCholinergic actionCholinergic inhibitionCholinergic inputMuscarinic receptorsBurst dischargesExcitatory modulatorThalamic neuronesNervous systemSpike activityFiring patternsPotassium conductanceReticular neuronesAcetylcholineNeuronesReticular systemInhibitory mechanism