2004
Chapter 5 Membrane Potential and Action Potential
McCormick D. Chapter 5 Membrane Potential and Action Potential. 2004, 115-140. DOI: 10.1016/b978-012148660-0/50006-8.Peer-Reviewed Original Research
2003
Adaptation and Temporal Decorrelation by Single Neurons in the Primary Visual Cortex
Wang X, Liu Y, Sanchez-Vives M, McCormick D. Adaptation and Temporal Decorrelation by Single Neurons in the Primary Visual Cortex. Journal Of Neurophysiology 2003, 89: 3279-3293. PMID: 12649312, DOI: 10.1152/jn.00242.2003.Peer-Reviewed Original ResearchConceptsPrimary visual cortical neuronsVisual cortical slicesCellular mechanismsVisual cortical neuronsIntrinsic membrane propertiesPrimary visual cortexPossible cellular mechanismsSensory inputSlow afterhyperpolarizationIntrinsic ionic currentsCortical slicesLayer 2/3Cortical neuronsNeocortical neuronsIntracellular injectionV1 neuronsNeuronal responsesVisual cortexEfficient neural codingModel neuronsReal-world sensory inputsNeuronsIonic currentsProlonged changesSingle neurons
2000
Cellular Mechanisms of Long-Lasting Adaptation in Visual Cortical Neurons In Vitro
Sanchez-Vives M, Nowak L, McCormick D. Cellular Mechanisms of Long-Lasting Adaptation in Visual Cortical Neurons In Vitro. Journal Of Neuroscience 2000, 20: 4286-4299. PMID: 10818164, PMCID: PMC6772630, DOI: 10.1523/jneurosci.20-11-04286.2000.Peer-Reviewed Original ResearchConceptsSpike frequency adaptationSlow afterhyperpolarizationCortical neuronsFerret primary visual cortexProlonged dischargeCellular mechanismsVisual cortical neuronsPrimary visual cortexSlow spike frequency adaptationIntracellular recordingsIntracellular injectionRightward shiftAfterhyperpolarizationVisual cortexReversal potentialContrast adaptationNeuronsDischarge frequencyMembrane conductanceVivoVisual systemBlockadeCortexImportant role
1994
Sensory gating mechanisms of the thalamus
McCormick D, Bal T. Sensory gating mechanisms of the thalamus. Current Opinion In Neurobiology 1994, 4: 550-556. PMID: 7812144, DOI: 10.1016/0959-4388(94)90056-6.Peer-Reviewed Original ResearchConceptsCerebral cortexThalamocortical circuitsRole of GABAASleep-wake cycleGABAB receptorsNeurotransmitter systemsThalamocortical activityAbnormal functionThalamusSensory-motor informationDense projectionsCortexAbnormal patternsCellular mechanismsVivo investigationsSensory informationGABAABrainstemReceptors
1993
Cellular Mechanisms of a Synchronized Oscillation in the Thalamus
von M, Bal T, McCormick D. Cellular Mechanisms of a Synchronized Oscillation in the Thalamus. Science 1993, 261: 361-364. PMID: 8392750, DOI: 10.1126/science.8392750.Peer-Reviewed Original ResearchConceptsInhibitory postsynaptic potentialsSpindle wavesPostsynaptic potentialsAbsence seizuresRelay cellsFerret lateral geniculate nucleusRhythmic population activityGABAB inhibitory postsynaptic potentialsReceptor-mediated inhibitionSeizure-like activityLateral geniculate nucleusGABAB receptorsRebound burstsGABAB antagonistRelay neuronsPerigeniculate nucleusGeniculate nucleusPharmacological blockNeuronal activityCortical systemsCellular mechanismsPopulation activitySeizuresCellsThalamus
1989
Noradrenaline and serotonin selectively modulate thalamic burst firing by enhancing a hyperpolarization-activated cation current
Pape H, McCormick D. Noradrenaline and serotonin selectively modulate thalamic burst firing by enhancing a hyperpolarization-activated cation current. Nature 1989, 340: 715-718. PMID: 2475782, DOI: 10.1038/340715a0.Peer-Reviewed Original ResearchConceptsThalamic neuronsRhythmic burstsAction potentialsHyperpolarization-activated cation currentSingle spike activityGenerate action potentialsSlow-wave sleepSingle-spike firingState of excitabilityAction potential generationSerotonergic inputNeurons displaySynaptic processingSpike activityCation currentThalamic burstsSpike firingNoradrenalineSerotoninCellular mechanismsNeuronsRhythmic oscillationsNovel actionBehavioral statesCyclic AMP