2024
Neural correlates of proactive avoidance deficits and alcohol use motives in problem drinking
Le T, Oba T, Couch L, McInerney L, Li C. Neural correlates of proactive avoidance deficits and alcohol use motives in problem drinking. Translational Psychiatry 2024, 14: 336. PMID: 39168986, PMCID: PMC11339324, DOI: 10.1038/s41398-024-03039-y.Peer-Reviewed Original ResearchConceptsAvoidance deficitNegative emotionsDrinking motivesAlcohol useNeural correlatesProblem drinkingRight anterior insula activityAssociated with greater alcohol useAnterior insula activityAlcohol use motivesGreater alcohol useProblem drinking groupInfluence alcohol usePhysical painInsula activationDrinking severityGo/NoGo taskNeural underpinningsPutamen responseSocial drinkersBehavioral measuresAvoidance performanceBehavioral resultsFunctional connectivityDrinking behavior
2020
Predicting alcohol dependence from multi‐site brain structural measures
Hahn S, Mackey S, Cousijn J, Foxe JJ, Heinz A, Hester R, Hutchinson K, Kiefer F, Korucuoglu O, Lett T, Li C, London E, Lorenzetti V, Maartje L, Momenan R, Orr C, Paulus M, Schmaal L, Sinha R, Sjoerds Z, Stein DJ, Stein E, van Holst R, Veltman D, Walter H, Wiers RW, Yucel M, Thompson PM, Conrod P, Allgaier N, Garavan H. Predicting alcohol dependence from multi‐site brain structural measures. Human Brain Mapping 2020, 43: 555-565. PMID: 33064342, PMCID: PMC8675424, DOI: 10.1002/hbm.25248.Peer-Reviewed Original ResearchConceptsAlcohol dependenceRight lateral orbitofrontal cortexLeft superior frontal gyrusCurrent alcohol dependenceTransverse temporal gyrusENIGMA Addiction Working GroupInclusion of casesSuperior frontal gyrusStructural magnetic resonanceCortical surface areaRight transverse temporal gyrusLateral orbitofrontal cortexBrain structural measuresCortical thicknessPutamen volumePotential biomarkersKTN1 variants and risk for attention deficit hyperactivity disorder
Luo X, Guo X, Tan Y, Zhang Y, Garcia‐Milian R, Wang Z, Shi J, Yu T, Ji J, Wang X, Xu J, Zhang H, Zuo L, Lu L, Wang K, Li C. KTN1 variants and risk for attention deficit hyperactivity disorder. American Journal Of Medical Genetics Part B Neuropsychiatric Genetics 2020, 183: 234-244. PMID: 32190980, PMCID: PMC7210069, DOI: 10.1002/ajmg.b.32782.Peer-Reviewed Original ResearchSignificant, replicable, and functional associations between KTN1 variants and alcohol and drug codependence
Luo X, Guo X, Luo X, Tan Y, Zhang P, Yang K, Xie T, Shi J, Zhang Y, Xu J, Zuo L, Li C. Significant, replicable, and functional associations between KTN1 variants and alcohol and drug codependence. Addiction Biology 2020, 26: e12888. PMID: 32115811, PMCID: PMC7641293, DOI: 10.1111/adb.12888.Peer-Reviewed Original Research
2009
Altered Impulse Control in Alcohol Dependence: Neural Measures of Stop Signal Performance
Li C, Luo X, Yan P, Bergquist K, Sinha R. Altered Impulse Control in Alcohol Dependence: Neural Measures of Stop Signal Performance. Alcohol Clinical And Experimental Research 2009, 33: 740-750. PMID: 19170662, PMCID: PMC2697053, DOI: 10.1111/j.1530-0277.2008.00891.x.Peer-Reviewed Original ResearchConceptsHealthy control subjectsFunctional magnetic resonance imagingAlcohol dependencePost-error behavioral adjustmentDorsolateral prefrontal cortexAlcohol urgesTrial reaction timePost-error slowingPrefrontal cortexLeft dorsolateral prefrontal cortexRight dorsolateral prefrontal cortexMagnetic resonance imagingImpulse controlStatistical parametric mappingStop errorAbstinent patientsControl subjectsNovel pharmacotherapiesSignal reaction timeTreatment outcomesFrontal cortexHC subjectsResonance imagingBehavioral adjustmentSubcortical structures
2000
Impairment of motor imagery in putamen lesions in humans
Li C. Impairment of motor imagery in putamen lesions in humans. Neuroscience Letters 2000, 287: 13-16. PMID: 10841979, DOI: 10.1016/s0304-3940(00)01164-2.Peer-Reviewed Original ResearchConceptsMotor imageryMotor cortex involvementMovement imagery tasksMemory processesVisual imageryImagery tasksCortex involvementEnd posturesPutamen lesionsCortical lesionsCortical patientsCortical structuresTaskImageryBasal gangliaNeural networkPutamenLesionsFirst movementPatientsImpairmentMovementGangliaThird party