The Effects of Methylphenidate on Resting-State Functional Connectivity of the Basal Nucleus of Meynert, Locus Coeruleus, and Ventral Tegmental Area in Healthy Adults
Kline RL, Zhang S, Farr OM, Hu S, Zaborszky L, Samanez-Larkin GR, Li CS. The Effects of Methylphenidate on Resting-State Functional Connectivity of the Basal Nucleus of Meynert, Locus Coeruleus, and Ventral Tegmental Area in Healthy Adults. Frontiers In Human Neuroscience 2016, 10: 149. PMID: 27148006, PMCID: PMC4834346, DOI: 10.3389/fnhum.2016.00149.Peer-Reviewed Original ResearchResting-state functional connectivityEffects of methylphenidateAttention deficit hyperactivity disorderLocus coeruleusPositive connectivityNegative connectivityFunctional connectivityBrain resting-state functional connectivityHealthy adultsDeficit hyperactivity disorderBasal nucleusDose of methylphenidateMiddle occipital gyrusSeed regionVTA/SNcVentral tegmental area/substantia nigraCognitive controlVentral tegmental areaHyperactivity disorderOccipital gyrusT-testCatecholaminergic signalingTwo-sample t-testMethylphenidatePrecentral gyrus