The dorsolateral prefrontal cortex is selectively involved in chemotherapy-related cognitive impairment in breast cancer patients with different hormone receptor expression.
Chen H, Ding K, Zhao J, Chao HH, Li CR, Cheng H. The dorsolateral prefrontal cortex is selectively involved in chemotherapy-related cognitive impairment in breast cancer patients with different hormone receptor expression. American Journal Of Cancer Research 2019, 9: 1776-1785. PMID: 31497358, PMCID: PMC6726991.Peer-Reviewed Original ResearchChemotherapy-related cognitive impairmentBreast cancer patientsHormone receptor expressionDorsolateral prefrontal cortexLeft dorsolateral prefrontal cortexCancer patientsSuperior frontal gyrusReceptor expressionFunctional connectivityPrefrontal cortexEstrogen receptorLeft precuneusCognitive impairmentFunctional magnetic resonance imaging (fMRI) examinationsMagnetic resonance imaging examinationsRight superior frontal gyrusNeuropsychological testsRight dorsolateral prefrontal cortexFunctional connectivity strengthResting-state fMRI dataER-/PRBC patientsDLPFC connectivityBreast cancerImaging examinations