2023
Resting-State Functional Connectivity of the Dorsal and Ventral Striatum, Impulsivity, and Severity of Use in Recently Abstinent Cocaine-Dependent Individuals
Dong X, Zhornitsky S, Wang W, Le T, Chen Y, Chaudhary S, Li C, Zhang S. Resting-State Functional Connectivity of the Dorsal and Ventral Striatum, Impulsivity, and Severity of Use in Recently Abstinent Cocaine-Dependent Individuals. The International Journal Of Neuropsychopharmacology 2023, 26: 627-638. PMID: 37579016, PMCID: PMC10519818, DOI: 10.1093/ijnp/pyac019.Peer-Reviewed Original ResearchConceptsResting-state functional connectivityInferior frontal cortexCocaine-dependent individualsHealthy controlsVentral striatumCocaine useDorsal striatumAbstinent cocaine-dependent individualsCocaine misuseFunctional connectivityYears of drinkingLeft orbitofrontal cortexBIS-11 scoresRecent cocaine useLeft inferior frontal cortexDopaminergic deficitCortex connectivityFrontal cortexSeparate cohortHuman studiesSeverity of useAnimal studiesSecond cohortOrbitofrontal cortexBarratt Impulsivity Scale
2006
Antisocial personality and stress-induced brain activation in cocaine-dependent patients
Li CS, Kosten TR, Sinha R. Antisocial personality and stress-induced brain activation in cocaine-dependent patients. Neuroreport 2006, 17: 243-247. PMID: 16462591, DOI: 10.1097/01.wnr.0000199471.06487.a2.Peer-Reviewed Original ResearchConceptsCocaine-dependent individualsDistress processingBrain activationStress imageryAntisocial personalitySocialization scoresFunctional magnetic resonance imaging studyAbstinent cocaine-dependent individualsRegional brain activationStress-induced brain activationFemale participantsMedial prefrontal cortexMagnetic resonance imaging studyResonance imaging studyNeural correlatesLower socialization scoresCocaine-dependent patientsCorticolimbic brain regionsPrefrontal cortexImportant sex differencesBrain regionsPersonalityInterest analysisSignificant activationEffect size