2010
Age-induced disruption of selective olfactory bulb synaptic circuits
Richard MB, Taylor SR, Greer CA. Age-induced disruption of selective olfactory bulb synaptic circuits. Proceedings Of The National Academy Of Sciences Of The United States Of America 2010, 107: 15613-15618. PMID: 20679234, PMCID: PMC2932573, DOI: 10.1073/pnas.1007931107.Peer-Reviewed Original ResearchConceptsMouse OBLayer-specific alterationsAfferent synaptic inputExternal plexiform layerPrimary sensory cortexAge-related alterationsAge-related cognitive deficitsNeuronal lossOlfactory bulb circuitryProjection neuronsPlexiform layerOB glomeruliQuantitative morphometric analysisSynaptic densityGlomerular layerInterneuron subpopulationsOlfactory functionOSN axonsSynaptic inputsSensory cortexOB layersSynaptic circuitsSensory functionOB circuitryCognitive deficits
2007
Synaptic Integration of Adult-Generated Olfactory Bulb Granule Cells: Basal Axodendritic Centrifugal Input Precedes Apical Dendrodendritic Local Circuits
Whitman MC, Greer CA. Synaptic Integration of Adult-Generated Olfactory Bulb Granule Cells: Basal Axodendritic Centrifugal Input Precedes Apical Dendrodendritic Local Circuits. Journal Of Neuroscience 2007, 27: 9951-9961. PMID: 17855609, PMCID: PMC6672649, DOI: 10.1523/jneurosci.1633-07.2007.Peer-Reviewed Original ResearchConceptsExternal plexiform layerGranule cell layerAdult-generated granule cellsGranule cellsOlfactory bulbSynaptic integrationLocal circuitsOlfactory bulb granule cellsNew granule cellsSubventricular zone migrateAdult mammalian olfactory bulbMammalian olfactory bulbElaborate dendritic arborsBasal dendritesPostsynaptic markersAxon collateralsSynaptic markersPlexiform layerPeriglomerular cellsDendritic arborsMitral/Spine increasesDendritic spinesNew interneuronsD postinfection