2024
β1-adrenoceptor expression on GABAergic interneurons in primate dorsolateral prefrontal cortex: potential role in stress-induced cognitive dysfunction
Joyce M, Yang S, Morin K, Duque A, Arellano J, Datta D, Wang M, Arnsten A. β1-adrenoceptor expression on GABAergic interneurons in primate dorsolateral prefrontal cortex: potential role in stress-induced cognitive dysfunction. Neurobiology Of Stress 2024, 30: 100628. PMID: 38550854, PMCID: PMC10973161, DOI: 10.1016/j.ynstr.2024.100628.Peer-Reviewed Original ResearchDorsolateral prefrontal cortexPrefrontal cortexStress-induced cognitive dysfunctionTreat stress-related disordersPrimate dorsolateral prefrontal cortexImpaired working memoryWorking memory deficitsWorking memory taskCalcium-binding proteins calbindinStress-related disordersClasses of inhibitory neuronsLevels of norepinephrineFast-spikingMemory taskDopamine releaseWorking memoryMemory deficitsInhibitory neuronsCognitive dysfunctionPV interneuronsGABAergic interneuronsDlPFCBehavior analysisCortexPyramidal cells
2006
The effects of sex and hormonal status on restraint-stress-induced working memory impairment
Shansky RM, Rubinow K, Brennan A, Arnsten A. The effects of sex and hormonal status on restraint-stress-induced working memory impairment. Behavioral And Brain Functions 2006, 2: 8. PMID: 16522198, PMCID: PMC1420310, DOI: 10.1186/1744-9081-2-8.Peer-Reviewed Original ResearchRestraint stressStress-related disordersPrefrontal cortexFemale ratsHormonal statusCognitive functionPFC cognitive functionAcute restraint stressHigh estrogen levelsMajor depressive disorderMinutes of restraintMethodsThe present studyDendritic remodelingEstrogen levelsDepressive disorderMale ratsPharmacological stressorHormonal influencesMemory impairmentHippocampal functionSignificant impairmentNeuronal morphologyConclusionThese resultsEstrus phaseOestrous cycle