2020
Impact of intra-tumoral heterogeneity detected by next-generation sequencing on acute myeloid leukemia survival
Schulz WL, Rinder HM, Durant TJS, Tormey CA, Torres R, Smith BR, Hager KM, Howe JG, Siddon AJ. Impact of intra-tumoral heterogeneity detected by next-generation sequencing on acute myeloid leukemia survival. Leukemia & Lymphoma 2020, 61: 3269-3271. PMID: 32715805, DOI: 10.1080/10428194.2020.1797016.Peer-Reviewed Original Research
2019
A Message to Medical School Promotion Committees: Proper Credit for Peer-Reviewed Online Educational Materials.
Rifai N, Smith BR, Connelly MT. A Message to Medical School Promotion Committees: Proper Credit for Peer-Reviewed Online Educational Materials. Clinical Chemistry 2019, 65: 715-717. PMID: 31003977, DOI: 10.1373/clinchem.2019.305862.Peer-Reviewed Original Research
2018
False-Positive Light Chain Clonal Restriction by Flow Cytometry in Patients Treated With Alemtuzumab
Chen PP, Tormey CA, Eisenbarth SC, Torres R, Richardson SS, Rinder HM, Smith BR, Siddon AJ. False-Positive Light Chain Clonal Restriction by Flow Cytometry in Patients Treated With Alemtuzumab. American Journal Of Clinical Pathology 2018, 151: 154-163. PMID: 30307483, DOI: 10.1093/ajcp/aqy129.Peer-Reviewed Original ResearchConceptsHealthy donor bloodAlemtuzumab treatmentDonor bloodBone marrowFlow cytometryLight chain restrictionT-cell prolymphocytic leukemiaB-cell neoplasmsLight chain clonalityFlow cytometry analysisAutoimmune diseasesHematologic malignanciesImmunophenotypic analysisChain restrictionAlemtuzumabT cellsB cellsProlymphocytic leukemiaImmunoglobulin G1PatientsMonoclonal antibodiesCytometry analysisSimilar findingsBloodClonal restriction
2016
Laboratory Medicine Education at U.S. Medical Schools
Smith BR, Kamoun M, Hickner J. Laboratory Medicine Education at U.S. Medical Schools. Academic Medicine 2016, 91: 107-112. PMID: 26200574, PMCID: PMC5480607, DOI: 10.1097/acm.0000000000000817.Peer-Reviewed Original ResearchConceptsLaboratory medicine educationU.S. medical schoolsMedicine educationMedical schoolsCourse workNational standardized examinationsProblem-based learningPreclinical curriculumCurriculum guidelinesStudent competenciesStudent interestClinical curriculumEducation directorsMedical educationMedicine curriculumLack of knowledgeCurriculumLiaison CommitteeSchoolsEducationCompetency assessmentDepartment chairsLaboratory sessionsStandardized examinationCompetenciesOpportunity: Newly Created Physician-Scientist Research Pathway by the American Board of Pathology.
Remick DG, Lorenz RG, Smith BR. Opportunity: Newly Created Physician-Scientist Research Pathway by the American Board of Pathology. Academic Pathology 2016, 3: 2374289516632240. PMID: 28725759, PMCID: PMC5497862, DOI: 10.1177/2374289516632240.Peer-Reviewed Original Research
2015
Impact of Molecular Clonality on Survival in Acute Myeloid Leukemia
Schulz W, Durant T, Rinder H, Tormey C, Torres R, Smith B, Hager K, Howe J, Siddon A. Impact of Molecular Clonality on Survival in Acute Myeloid Leukemia. Blood 2015, 126: 1385. DOI: 10.1182/blood.v126.23.1385.1385.Peer-Reviewed Original ResearchDe novo acute myeloid leukemiaNovo acute myeloid leukemiaAcute myeloid leukemiaMolecular clonalityAML patientsTumor heterogeneityMyeloid leukemiaNext-generation sequencingNormal-risk subjectsAdverse prognostic indicatorTime of diagnosisFurther prospective studiesLong-term outcomesFLT3-ITD mutationHigh-risk groupChoice of therapyFirst prospective evidenceLimited clinical utilityHigh-risk classificationEarly survivalStudy patientsOverall survivalPatient agePatient subsetsInitial diagnosisBiosimilar biologics: never identical but close enough
Abi‐Raad R, Smith BR. Biosimilar biologics: never identical but close enough. Transfusion 2015, 55: 229-231. PMID: 25683185, DOI: 10.1111/trf.12961.Peer-Reviewed Original ResearchThe changing face of laboratory medicine: a more service and less academically oriented profession?
Scott MG, Rifai N, Smith B, Oellerich M, Panteghini M, Apple F, Sikaris K, Young I. The changing face of laboratory medicine: a more service and less academically oriented profession? Clinical Chemistry 2015, 61: 322-9. PMID: 25161143, DOI: 10.1373/clinchem.2014.230300.Peer-Reviewed Original Research
2014
In reply
Tormey CA, Smith BR. In reply. Transfusion 2014, 54: 1441-1442. PMID: 24819077, DOI: 10.1111/trf.12587.Peer-Reviewed Original ResearchHematology in Clinical Pathology
Torres R, Tormey C, Smith B. Hematology in Clinical Pathology. 2014, 3269-3286. DOI: 10.1016/b978-0-12-386456-7.06305-x.ChaptersRed blood cellsCoagulation factorsFunction of RBCsHematologic diagnosisUnderlying pathophysiologyCongenital/Hematologic diseasesLaboratory modalitiesClinical pathologyDiverse medical disciplinesBlood disordersLaboratory assaysBlood cellsDisordersPrimary aimMedical disciplinesDiagnosisHematologyNormal developmentAssaysNormal processCellular morphologyPathophysiologyWBCLeukocytes
2013
Chapter 52 Cardiopulmonary Bypass
Smith B, Rinder H. Chapter 52 Cardiopulmonary Bypass. 2013, 1075-1096. DOI: 10.1016/b978-0-12-387837-3.00052-3.Peer-Reviewed Original Research
2012
The transfusion medicine specialist as a coagulation consultant: a new variant of therapeutic pathology
Tormey CA, Smith BR. The transfusion medicine specialist as a coagulation consultant: a new variant of therapeutic pathology. Transfusion 2012, 53: 2086-2093. PMID: 23228202, DOI: 10.1111/trf.12012.Peer-Reviewed Original ResearchConceptsTransfusion medicine practitionersMedicine practitionersTransfusion medicineLaboratory coagulation testingRegular clinical practicePatient managementClinical roleCoagulation testingClinical practiceClinical issuesHemostasisShortage of specialistsField of hemostasisConsultationNovel curriculumMedicineThrombosisPathology Resident and Fellow Education in a Time of Disruptive Technologies
Ziai JM, Smith BR. Pathology Resident and Fellow Education in a Time of Disruptive Technologies. Clinics In Laboratory Medicine 2012, 32: 623-638. PMID: 23078663, DOI: 10.1016/j.cll.2012.07.004.Peer-Reviewed Original ResearchConceptsTraditional educational paradigmFellow educationPractice modelEducational paradigmPractice aspectsTraining programHeuristic needsDisruptive technologiesPathology residentsEducationMedical knowledgeInnovative methodologyPractice of pathologyNew medical knowledgeTechnologyTrainingProgramPracticeFutureExpertiseKnowledgeImplementationQuestionsNeedArticleNormalized CCND1 expression has prognostic value in mantle cell lymphoma
Siddon AJ, Torres R, Rinder HM, Smith BR, Howe JG, Tormey CA. Normalized CCND1 expression has prognostic value in mantle cell lymphoma. British Journal Of Haematology 2012, 158: 551-553. PMID: 22671703, DOI: 10.1111/j.1365-2141.2012.09181.x.Peer-Reviewed Original ResearchUtility of peripheral blood flow cytometry in differentiating low grade versus high grade myelodysplastic syndromes (MDS) and in the evaluation of cytopenias.
Rashidi HH, Xu X, Wang HY, Shafi NQ, Rameshkumar K, Messer K, Smith BR, Rose MG. Utility of peripheral blood flow cytometry in differentiating low grade versus high grade myelodysplastic syndromes (MDS) and in the evaluation of cytopenias. International Journal Of Clinical And Experimental Pathology 2012, 5: 224-30. PMID: 22558477, PMCID: PMC3341683.Peer-Reviewed Original ResearchConceptsHigh-grade myelodysplastic syndromeChronic myelomonocytic leukemiaPeripheral blood flow cytometryEvaluation of cytopeniasBlood flow cytometryMyelodysplastic syndromeFlow cytometryDifferential diagnosisHigh-risk myelodysplastic syndromeLow-grade myelodysplastic syndromesRisk myelodysplastic syndromesCMML patientsMyelomonocytic leukemiaDiagnostic utilityCytopeniasPatientsCytometrySyndromeLow gradeDiagnosisLeukemiaHow well are we training the next generation of clinical pathologists and clinical laboratory directors? A global perspective.
Scott MG, Smith BR, Wu AH, Young IS, Plebani M, Chiu RW. How well are we training the next generation of clinical pathologists and clinical laboratory directors? A global perspective. Clinical Chemistry 2012, 58: 491-5. PMID: 21969387, DOI: 10.1373/clinchem.2011.171199.Peer-Reviewed Original Research
2010
Laboratory medicine curriculum.
Klatt EC, Smith BR. Laboratory medicine curriculum. American Journal Of Clinical Pathology 2010, 134: 849. PMID: 20959671, DOI: 10.1309/AJCP1KKFJ2VLXUQL.Peer-Reviewed Original ResearchEducating Medical Students in Laboratory Medicine
Smith BR, Aguero-Rosenfeld M, Anastasi J, Baron B, Berg A, Bock JL, Campbell S, Crookston KP, Fitzgerald R, Fung M, Haspel R, Howe JG, Jhang J, Kamoun M, Koethe S, Krasowski MD, Landry ML, Marques MB, Rinder HM, Roberts W, Schreiber WE, Spitalnik SL, Tormey CA, Wolf P, Wu YY. Educating Medical Students in Laboratory Medicine. American Journal Of Clinical Pathology 2010, 133: 533-542. PMID: 20231605, DOI: 10.1309/ajcpqct94sferlni.Peer-Reviewed Original ResearchConceptsMedical student educationMedical school facultyClinical Laboratory PhysiciansCurriculum committeeStudent educationSuggested curriculumInstructional methodsFlexner ReportSchool facultyMedicine curriculumMedical studentsCurriculumAdequacy of trainingAreas of concernHelpful outlineNational health care organizationsTrainingLaboratory physiciansStudentsEducationFacultyDisciplinesAcademyEntire membershipTopic
2009
2008 ACLPS Panel Discussion on Resident Education in Clinical Pathology
Prak E, Young DS, Kamoun M, Nachamkin I, Alexander CB, Spitalnik SL, Peerschke EI, Smith BR. 2008 ACLPS Panel Discussion on Resident Education in Clinical Pathology. American Journal Of Clinical Pathology 2009, 131: 618-622. PMID: 19369619, DOI: 10.1309/ajcppi03hmyaaeoj.Peer-Reviewed Original ResearchThe utility of flow cytometric immunophenotyping in cytopenic patients with a non-diagnostic bone marrow: A prospective study
Truong F, Smith BR, Stachurski D, Cerny J, Medeiros LJ, Woda BA, Wang A. The utility of flow cytometric immunophenotyping in cytopenic patients with a non-diagnostic bone marrow: A prospective study. Leukemia Research 2009, 33: 1039-1046. PMID: 19232722, DOI: 10.1016/j.leukres.2009.01.012.Peer-Reviewed Original ResearchConceptsMyelodysplastic syndromeCytopenic patientsFlow cytometricPredictive valueGroup 1 patientsGroup 2 patientsHematology outpatient clinicBone marrow aspirateNegative predictive valuePositive predictive valueFCM resultsMedian followMyelomonocytic maturationAbnormal cytogeneticsBM examinationBM diseaseClinical entityOutpatient clinicProspective studyMedical causesMorphological dysplasiaClinical managementMarrow aspiratesIdiopathic cytopeniaPatients