2007
Rbm15 Modulates Notch-Induced Transcriptional Activation and Affects Myeloid Differentiation
Ma X, Renda MJ, Wang L, Cheng EC, Niu C, Morris SW, S. AS, Krause DS. Rbm15 Modulates Notch-Induced Transcriptional Activation and Affects Myeloid Differentiation. Molecular And Cellular Biology 2007, 27: 3056-3064. PMID: 17283045, PMCID: PMC1899951, DOI: 10.1128/mcb.01339-06.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsBasic Helix-Loop-Helix Transcription FactorsCell NucleusCHO CellsCricetinaeCricetulusDNA-Binding ProteinsDrosophila ProteinsGene Expression ProfilingHomeodomain ProteinsImmunoglobulin J Recombination Signal Sequence-Binding ProteinMiceMolecular Sequence DataMyeloid CellsMyelopoiesisNuclear ProteinsPromoter Regions, GeneticProtein BindingProtein Structure, TertiaryProtein TransportReceptors, NotchRNA, MessengerRNA, Small InterferingRNA-Binding ProteinsTranscription Factor HES-1Transcription, GeneticTranscriptional ActivationConceptsN-terminusPromoter activityMyeloid differentiationCell linesCell type-specific mannerMyeloid precursor cell linePrimary murine cellsType-specific mannerDominant negative effectStimulation of NotchHematopoietic cell linesHuman erythroleukemia cellsPrecursor cell lineMurine cell linesHematopoietic stem cellsTranscriptional activationHes1 transcriptionRNA interferenceErythroleukemia cellsFusion proteinHes1 promoter activityMurine cellsFusion partnerHematopoietic cellsRBM15
1995
Full-Length But Not Truncated CD34 Inhibits Hematopoietic Ceil Differentiation of Ml Cells
Fackler M, Krause D, Smith O, Civin C, May W. Full-Length But Not Truncated CD34 Inhibits Hematopoietic Ceil Differentiation of Ml Cells. Blood 1995, 85: 3040-3047. PMID: 7538813, DOI: 10.1182/blood.v85.11.3040.bloodjournal85113040.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAnimalsAntigens, CDAntigens, CD34Base SequenceCell DifferentiationGene Expression Regulation, LeukemicGrowth InhibitorsHematopoietic Stem CellsInterleukin-6Leukemia Inhibitory FactorLeukemia, MyeloidLymphokinesMacrophagesMiceMolecular Sequence DataPeptide FragmentsPhagocytosisRecombinant Fusion ProteinsTumor Cells, CulturedConceptsFull-length CD34Developmental stage-specific mannerM1 myeloid leukemia cellsTerminal myeloid differentiationMurine hematopoietic stemStage-specific mannerProgenitor cellsHematopoietic cell differentiationCD34 proteinNegative regulatory roleCytoplasmic tail domainMurine M1 myeloid leukemia cellsStem/progenitor cellsArrest phenotypeFunction of CD34Tail domainTerminal differentiationCell differentiationRegulatory roleMyeloid differentiationHematopoietic stemDomain regionLeukemia inhibitory factorHematopoietic cellsMyeloid leukemia cells