2003
Cotransplantation of human mesenchymal stem cells enhances human myelopoiesis and megakaryocytopoiesis in NOD/SCID mice
Angelopoulou M, Novelli E, Grove JE, Rinder HM, Civin C, Cheng L, Krause DS. Cotransplantation of human mesenchymal stem cells enhances human myelopoiesis and megakaryocytopoiesis in NOD/SCID mice. Experimental Hematology 2003, 31: 413-420. PMID: 12763140, DOI: 10.1016/s0301-472x(03)00042-0.Peer-Reviewed Original ResearchConceptsPeripheral blood stem cellsNOD/SCID miceMesenchymal stem cellsMSC cotransplantationTransplant recipientsSCID miceCotransplantation of MSCsHematopoietic stem cellsHuman peripheral blood stem cellsStem cellsAllogeneic transplant recipientsTransplantation of CD34Autologous transplant recipientsHuman mesenchymal stem cellsBlood stem cellsHuman cell engraftmentMarrow-derived stromal cellsBone marrow cellsPlatelet engraftmentHuman bone marrow cellsHuman hematopoietic stem cellsCotransplantationBone marrowMegakaryocytic engraftmentB lymphocytes
1999
Functional activity of murine CD34+and CD34− hematopoietic stem cell populations
Donnelly D, Zelterman D, Sharkis S, Krause D. Functional activity of murine CD34+and CD34− hematopoietic stem cell populations. Experimental Hematology 1999, 27: 788-796. PMID: 10340393, DOI: 10.1016/s0301-472x(99)00032-6.Peer-Reviewed Original ResearchConceptsHematopoietic stem cellsCD34-LinStem cellsMurine bone marrow cellsHematopoietic stem cell populationStem cell populationCD34- hematopoietic stem cellsCompetitive repopulation experimentsHuman hematopoietic stem cellsClinical transplantation protocolsLong-term engraftmentBone marrowMarrow repopulating cellsBone marrow cellsDistinct populationsRepopulation experimentsRepopulating cellsCell populationsBone marrow repopulating cellsCD34 cellsMarrow cellsCell numberCellsFunctional activityBone marrow reconstitution