1998
Differences in Platelet α-granule Release between Normals and Immune Thrombocytopenic Patients and between Young and Old Platelets
Rinder HM, Tracey JB, Recht M, DeCastro L, Rinder CS, McHugh C, Smith BR. Differences in Platelet α-granule Release between Normals and Immune Thrombocytopenic Patients and between Young and Old Platelets. Thrombosis And Haemostasis 1998, 80: 457-462. PMID: 9759627, DOI: 10.1055/s-0037-1615229.Peer-Reviewed Original ResearchConceptsImmune thrombocytopenic purpuraThrombin receptor agonist peptideAlpha-granule releaseITP patientsOld plateletsThrombocytopenic patientsImmune thrombocytopenic patientsPlatelet α-granule releaseΑ-granule releaseNormal human controlsMaintenance of hemostasisControl RPSerious bleedingThrombocytopenic purpuraMegakaryocytic hypoplasiaPatient groupReticulated plateletsNormal controlsPatientsPlatelet responseAgonist peptideYoung plateletsPlateletsHemostatic activityCD62P
1993
Reticulated platelets in the evaluation of thrombopoietic disorders.
Rinder HM, Munz UJ, Ault KA, Bonan JL, Smith BR. Reticulated platelets in the evaluation of thrombopoietic disorders. Archives Of Pathology & Laboratory Medicine 1993, 117: 606-10. PMID: 8503732.Peer-Reviewed Original ResearchConceptsImmune platelet destructionImmune thrombocytopeniaPlatelet destructionNormal subjectsImmune thrombocytopenic purpuraThird of patientsSubset of patientsPlatelet determinationAbsence of megakaryocytesPlatelet-associated IgGChemotherapy-induced thrombocytopeniaInvasive diagnostic testsPeripheral blood plateletsFlow cytometric assayIgG levelsThrombocytopenic purpuraReticulated plateletsImmune destructionPlatelet valuesPatientsPlatelet IgGBone marrowThrombocytopeniaIgG dataLaboratory diagnosis