American College of Cardiology 71st Annual Scientific Session & Expo sessions announced

Yale Cardiovascular Medicine researchers will present at the American College of Cardiology (ACC) 71st Annual Scientific Session & Expo in Washington, DC, April 2 – 4, 2022. The conference brings together clinicians and researchers to promote basic, clinical and population science in cardiovascular research.

Research and session highlights include:

Late-Breakers

Yale faculty discuss groundbreaking clinical research at ACC 22.

• PROMPT-HF: A Cluster-Randomized PRagmatic Trial Aimed at ImprOving Use of Guideline Directed Medical Therapy in OutPatienTs With Heart Failure
• Featured Clinical Research II: Residual Leaks Post Left Atrial Appendage Occlusion
• Late-Breaking Clinical Trials Deep Dive II: A Randomized Trial To Confirm The Safety And Effectiveness Of Chocolate Touch Paclitaxel Coated PTA Balloon Catheter In Above The Knee Lesions

Saturday, April 2, 2022

52-13: Bringing Psychological Health into the Conversation

Erica Spatz

605-09: Remote Physiologic Monitoring: How Do We Handle the Data?

Erica Spatz

649-05: Nuclear: SPECT & PET, Modern Evolution of Old Ideas

Edward Miller

1000-17: Periprocedural Pericardial Effusion Complicating Transcatheter Left Atrial Appendage Occlusion: A Report from the NCDR LAAO Registry

Matthew J. Price, Miguel Valderrabano, Sarah Zimmerman, Daniel J. Friedman, Jeptha P. Curtis, Frederick A. Masoudi, James V. Freeman

1019-05: National Patterns of Eligibility for And Utilization of FDA-Approved Weight-Loss Agents Among US Adults, 2015-2018

Patrick Christopher Demkowicz, Arash A. Nargesi, Rohan Khera

1019-09: U.S. Patterns of Drug Utilization and Prescription Fills for Proven Cardioprotective Anti-Hyperglycemic Agents

Arash Aghajani Nargesi, Callahan Clark, Mengni Liu, Lian Chen, Abraham Reddy, Samuel Amodeo, Evangelos K. Oikonomou, Marc Suchard, Kasia Lipska, Darren K. McGuire, Zhenqiu Lin, Silvio E. Inzucchi, Harlan M. Krumholz, Rohan Khera

1024-07: Lower-Extremity Symptoms and Ankle-Brachial Index Screening as Predictors of Cardiovascular Outcomes in Black Adults: Insights from The Jackson Heart Study

Megan Lee, Kim G. E. Smolderen, Kristie Harris, Gaelle Romain, Lindsey Scierka, Jeremy Provance, Carlos Mena-Hurtado

1068-07: National Patterns of Eligibility and Use of Novel Lipid Lowering Therapies in the United States

Miles Shen, Arash Aghajani Nargesi, Khurram Nasir, Rohan Khera

1202-004: Rates of Guideline Directed Medical Therapy in Patients with Critical Limb Ischemia Undergoing Major Amputation: Insights from The National Cerner Health Facts Electronic Health Record Database

Jeremy Provance, John A. Spertus, Mark Hoffman, Philip Jones, Matthew C. Bunte, Todd Vogel, Carlos Mena-Hurtado, Kim G. E. Smolderen

1204-003: Patient Profiles and Trends in Peripheral Artery Disease and Microvascular Disease: A Retrospective Analysis

Miguel Algara, Paulina Luna, Kristie Harris, Waleed Tariq, Kim G. E. Smolderen, Carlos Mena-Hurtado

1174-009: Impact of Ischemic Heart Disease on Outcomes in Patients with Acute Respiratory Distress Syndrome

Max Biondi, Snigdha Jain, Michael A. Fuery, Alexander W. Thomas, Tariq Ali, Carlos Leon Alviar, Nihar R. Desai, P. Elliott Miller

1189-002: Comprehensive Comparative Effectiveness and Safety of First-Line Calcium Channel Blocker Monotherapy in Hypertensive Patients: A Large-Scale Multinational Participant-Level Assessment

Yuan Lu, Rohan Khera, Yuntian Liu, Ruijun Chen, Martijn Schuemie, George Hripcsak, Marc Suchard, Harlan M. Krumholz

1189-007: Comprehensive Comparative Effectiveness and Safety of First-Line Antihypertensive Monotherapy in Hypertensive Patients: A Large-Scale Multinational Participant-Level Assessment

Yuan Lu, Rohan Khera, Yuntian Liu, Ruijun Chen, Martijn Schuemie, George Hripcsak, Marc Suchard, Harlan M. Krumholz

1334-060: Association Between Accountable Care Organization Participation and Quality of Outpatient Cardiovascular Care

Erica Sarah Spatz, Kensey Gosch, Philip Jones, Thomas M. Maddox, Nihar R. Desai

1336-079: Carotid Artery Stenting and Angioplasty with Protection in Patients at High-Risk for Endarterectomy: Sapphire Worldwide Registry Outcomes Across Patient Subgroups

Kristie Harris, Carlos Mena-Hurtado, Kim G. E. Smolderen

1337-088: Perception of Illness Stratified by Invasive Phenotype in Women with Ischemia and No Obstructive Coronary Artery Disease

Leslie Yingzhijie Tseng, Nukte Goc, Steffne Kunnirickal, Natalija Odanovic, Alexandra Schwann, Emily J. Cherlin, Leslie Curry, Erica Sarah Spatz, Samit Shah

1360-109: Predictors of Poor Outcomes Among Patients Undergoing Catheter-Directed Thrombolysis for Deep Vein Thrombosis

Aneil Bhalla, Zain Ahmed, Carlos Mena-Hurtado, Robert Attaran

Sunday, April 3, 2022

406-12: A Cluster-Randomized PRagmatic Trial Aimed At ImprOving Use Of Guideline Directed Medical Therapy In OutPatienTs With Heart Failure: PROMPT-HF

Lama Ghazi, Yamamoto Yu, Simonov Michael, Kyle O’Connor, Ralph Riello, Joanna Huang, Temitope Olufade, James McDermott, Allen Hsiao, Nitu Kashyap, Fan Li, Melissa Martin, Claudia Coronel-moreno, Carlos Paredes, Eric Velazquez, Silvio Inzucchi, Francis P. Wilson, Nihar Desai, Tariq Ahmad

407-10: Residual Leaks Post Left Atrial Appendage Occlusion

Mohamad Adnan Alkhouli, Chengan Du, Ammar M. Killu, Trevor J. Simard, Peter A. Noseworthy, Paul A. Friedman, Jeptha P. Curtis, James V. Freeman, David R. Holmes, JR

697-08: Alternatives to Oral Anticoagulation

James V. Freeman

An introduction to the key aspects of clinical evaluation and management presented in the expert consensus decision pathway on cardiovascular sequelae of COVID-19 in adults.

781-11: Post-acute Sequelae of COVID-19

Erica Spatz

903-04: National Medicare Formulary Coverage and Out-Of-Pocket Costs of Quadruple Therapy for Heart Failure with Reduced Ejection Fraction

Kamil Faridi, Elias Dayoub, Joseph S. Ross, Sanket Shishir Dhruva, Nihar R. Desai

906-10: Representativeness of Peripheral Artery Disease Randomized Clinical Trials Supporting Current Guideline Recommendations

Yulanka Castro Dominguez, Carlos Mena Hurtado, Vanessa Obas, Miguel Algara, Zain Ahmed, Kim G. E. Smolderen

1073-03: Clinical Predictors of Embolic Burden After TAVR: An Analysis of the Safepass 2 Clinical Study

Alexandra J. Lansky, Jonathon White, James T. Stewart, James W. H. Blake, David Smyth, Sanjeevan Pasupati, Rajesh Nair, Helen Parise, Cody Pietras, Mark W. I. Webster, Rika Kawakami, Renu Virmani, Jonathon Leipsic

1086-03: Carotid Artery Stenting and Angioplasty with Protection in Patients At High-Risk For Endarterectomy: Sapphire Worldwide Registry Outcomes Across Patient Subgroups

Kristie Harris, Kim G. E. Smolderen, Carlos Mena-Hurtado

1379-085: Duration of Symptoms and Use of Diagnostic Testing in Patients with Ischemia and No Obstructive Coronary Artery Disease

Alexandra N. Schwann, Steffne Kunnirickal, Natalija Odanovic, Leslie Yingzhijie Tseng, Erica Sarah Spatz, Steven E. Pfau, Samit Shah

1379-089: Days Alive Out of Hospital for Patients with Left Ventricular Dysfunction and Coronary Artery Disease Treated with Coronary Artery Bypass Surgery or Medical Therapy: Findings from the Stich Trial

Kamil Faridi, Haocheng Huang, Helen Parise, Tariq Ahmad, Makoto Mori, Mabel Chung, Robert W. Yeh, Eric J. Velazquez

1388-140: Personalizing The Therapeutic Benefit From Spironolactone In Heart Failure With Preserved Ejection Fraction Through Computational Phenomaps Of The Topcat Trial And Machine Learning

Evangelos K. Oikonomou, Marc Suchard, Rohan Khera

1388-143: Identification Of Heart Failure with Reduced Ejection Fraction From Hospitalization Discharge Summaries Using Natural Language Processing

Astrid Hengartner, Benjamin Rosand, Philip Adejumo, Lian Chen, Arash A. Nargesi, Rohan Khera

1435-080: Prognostic Validity of Frailty Assessment Tools in Prediction of Mortality and Major Amputation in Patients Undergoing Revascularization for Lower Extremity Arterial Disease

Roozbeh Nikooie, Kim G. E. Smolderen, Mohammed Al-Damluji, Can Meng, Feng Dai, Michael Nanna, Bauer E. Sumpio, Peter Henke, Carlos Mena-Hurtado

1460-119: Myocardial Impact of Clonal Hematopoiesis of Indeterminate Potential (CHIP) Secretomes in Cardio-Oncology Patients

Jennifer Kwan, Jennifer Vanoudenhove, Saiti Halder, Giulia Biancon, Kanika Jain, Raja Chakraborty, Maryam Lustberg, Lajos Pusztai, Stuart Campbell, Hongyu Zhao, Stephanie Halene, John Hwa

Monday, April 4, 2022

410-16: A Randomized Trial To Confirm The Safety And Effectiveness Of Chocolate Touch Paclitaxel Coated PTA Balloon Catheter In Above The Knee Lesions

Mehdi H. Shishehbor, Thomas Zeller, Martin Werner, Marianne Brodmann, Helen Parise, Andrew Holden, Michael Lichtenberg, Sahil A. Parikh, Vikram Kashyap, Cody Pietras, Shiva Ardakani, Ulrich Beschorner, Prakash Krishnan, Khusrow A. K. Niazi, Andreas U. Wali, Alexandra J. Lansky

413-15/16: A Randomized Trial To Confirm The Safety And Effectiveness Of Chocolate Touch Paclitaxel Coated PTA Balloon Catheter In Above The Knee Lesions

Alexandra J. Lansky, Elissa Altin

917-04: Patient-facing mHealth application improves self-care and symptoms of heart failure in Uganda

Jeremy Schwartz, Sahr Wali, Martha Nabadda, Cinderella Ngonzi Muhangi, Ann R. Akiteng, Kaicheng Wang, Rebecca Gillman, J. Lucian Davis, Enock Kibalizi, Nelson Sewankambo, Peter S. Lwabi, Christine Nalwadda, Heather Joan Ross, Joseph Cafazzo, Isaac Ssinabulya

1114-07: Healthcare Resource Use, Intensity and Costs Among Patients with Heart Failure with Reduced Ejection Fraction Treated with Omecamtiv Mecarbil in Galactic-HF

Nihar R. Desai, Rafael Diaz, Michael Felker, Marco Metra, Scott D. Solomon, Gary Binder, Punag Divanji, Daniel Gomes, Robb D. Kociol, Lisa Meng, John R. Teerlink

1524-133: Underrepresentation and Exclusion of Patients with Cardiovascular Disease in Intensive Care Randomized Control Trials

Tariq Ali, Alyssa Grimshaw, Alexander W. Thomas, Michael A. Solomon, Harlan M. Krumholz, Joseph S. Ross, P. Elliott Miller

1539-103: Trends in Carotid Artery Revascularization: An Analysis from the National Readmission Database

Waleed Tariq Siddiqui, Miguel Algara, Pragati Bogra, Kristie Harris, Kim G. E. Smolderen, Carlos Mena Hurtado

1542-133: Racial Disparities in Unexplained Left Ventricular Hypertrophy

Avinainder Singh, Kristie Harris, Daniel Jacoby, Edward James Miller

1542-141: Unexplained Amyloid Screening and Treatment Drop off in Patients with Left Ventricular Hypertrophy

Kristie Harris, Daniel Jacoby, Avinainder Singh, Matthew M. Burg, Oyere Onuma, Cesia Gallegos Kattan, Tiantian Shi, Edward Miller

2004-131: Adverse Cardiovascular Events Associated with Kinase Inhibitors in the Treatment of Cancer Reveal Specific Risk Based on thr Kinase Inhibitor - A Single-Center Retrospective Cohort Study

Jennifer Kwan, Miles Shen, Michael Mankbadi, Peter Wang, Saif Zaman, Seohyuk Lee, Matthew Jiang, Weiwei Tao, Wei Wei, Narjes Akhlaghi, Lauren Anne Baldassarre

2004-132: Adverse Cardiovascular Events Associated with Immune Checkpoint Inhibitors - A Single Center Retrospective Cohort Study

Jennifer Kwan, Narjes Akhlaghi, Matthew Jiang, Miles Shen, Yunju Im, Michael Mankbadi, Peter Wang, Saif Zaman, Seohyuk Lee, Weiwei Tao, Wei Wei, Shuangge Ma, Lauren Anne Baldassarre