2024
Impact of setup errors on the robustness of linac‐based single‐isocenter coplanar and non‐coplanar VMAT plans for multiple brain metastases
Sun X, Guan F, Yun Q, Jennings M, Biggs S, Wang Z, Wang W, Zhang T, Shi M, Zhao L. Impact of setup errors on the robustness of linac‐based single‐isocenter coplanar and non‐coplanar VMAT plans for multiple brain metastases. Journal Of Applied Clinical Medical Physics 2024, 25: e14317. PMID: 38439583, PMCID: PMC11244668, DOI: 10.1002/acm2.14317.Peer-Reviewed Original ResearchNon-coplanar plansPlanning target volumeGross tumor volumePatient setup errorsPlan evaluation metricsSetup errorsMultiple brain metastasesImpact of setup errorsNon-coplanar VMAT plansDose delivery accuracyGamma passing ratesRobust treatment plansModified plansSingle-isocenterVMAT plansGamma analysisRotation errorBrain metastasesDose coverageLinac-basedTreatment planningDelivery accuracyTarget volumePrescribed doseNon-coplanar
2020
Dosimetric and Radiobiological Comparison of Five Techniques for Postmastectomy Radiotherapy with Simultaneous Integrated Boost
Tang D, Liang Z, Guan F, Yang Z. Dosimetric and Radiobiological Comparison of Five Techniques for Postmastectomy Radiotherapy with Simultaneous Integrated Boost. BioMed Research International 2020, 2020: 9097352. PMID: 32775448, PMCID: PMC7391102, DOI: 10.1155/2020/9097352.Peer-Reviewed Original ResearchConceptsNormal tissue complication probabilitySimultaneous integrated boostHighest normal-tissue complication probabilityPostmastectomy radiotherapyIntegrated boostLeft-sided breast cancer treatmentComplication probabilityHybrid intensity-modulated radiotherapyLeft-sided breast cancerSimilar dosimetric resultsSuperior dose sparingBetter dose coverageBetter conformity indexBreast cancer treatmentIntensity-modulated radiotherapyOAR mean doseContralateral breastMean doseTD plansBreast cancerConformity indexRadiobiological comparisonDose sparingDose coverageClinical practice
2019
Potential for Improvements in Robustness and Optimality of Intensity-Modulated Proton Therapy for Lung Cancer with 4-Dimensional Robust Optimization
Ge S, Wang X, Liao Z, Zhang L, Sahoo N, Yang J, Guan F, Mohan R. Potential for Improvements in Robustness and Optimality of Intensity-Modulated Proton Therapy for Lung Cancer with 4-Dimensional Robust Optimization. Cancers 2019, 11: 35. PMID: 30609652, PMCID: PMC6356681, DOI: 10.3390/cancers11010035.Peer-Reviewed Original ResearchLung cancer patientsIntensity-modulated proton therapyCancer patientsIMPT dose distributionsClinical target volume coverageNormal tissue dose distributionsTarget volume coveragePlanning target volumeTarget dose coverageConventional planning target volumeRespiratory motionDose distributionDifferent tumor sizesTarget dose distributionProton therapyTumor sizeLung cancerDose coverageTreatment planIMPT plansTarget volumeNormal tissuesVolume coverageRespiratory phasesPatients