2002
Cortisol modulation of 5-HT-mediated growth hormone release in recovered depressed patients
Bhagwagar Z, Hafizi S, Cowen P. Cortisol modulation of 5-HT-mediated growth hormone release in recovered depressed patients. Journal Of Affective Disorders 2002, 72: 249-255. PMID: 12450642, DOI: 10.1016/s0165-0327(01)00467-0.Peer-Reviewed Original ResearchConceptsGrowth hormone releaseDepressed patientsMajor depressionHormone releaseStress-induced cortisol secretionBrain serotonin functionPlasma GH levelsEffects of cortisolEffect of hydrocortisoneCross-over designStressful life eventsGH responseGH levelsSingle doseCortisol secretionGH releaseHealthy controlsSerotonin functionRecurrent depressionTRP infusionHealthy volunteersCortisol modulationDepressive symptomatologyDepressed subjectsEuthymic subjects
2000
Modelling a loss event: effect of imagined bereavement on the hypothalamic–pituitary–adrenal axis
McCLEERY J, BHAGWAGAR Z, SMITH K, GOODWIN G, COWEN P. Modelling a loss event: effect of imagined bereavement on the hypothalamic–pituitary–adrenal axis. Psychological Medicine 2000, 30: 219-223. PMID: 10722192, DOI: 10.1017/s0033291799001361.Peer-Reviewed Original ResearchConceptsNegative mood induction procedureNegative mood inductionMood induction procedureMood inductionRelevant psychosocial stressorsIndividual differencesCortisol responseSalivary cortisol responseTransient moodPsychological stateInduction procedureAcute cortisol responsePsychosocial stressorsMood disorders researchDisorder researchCortisol outputStressorsBereavementNeuroendocrine responsesMoodAdrenal axisDepressive illnessHealthy volunteersMusicImportant mediator