2007
Bipolar disorder: the neglected psychosis
Bhagwagar Z, Goodwin G. Bipolar disorder: the neglected psychosis. Psychiatry 2007, 6: 389-392. DOI: 10.1016/j.mppsy.2007.06.005.Peer-Reviewed Original ResearchBipolar disorderAnti-manic actionMainstay of treatmentNon-pharmacological interventionsLong-term treatmentStage of illnessRole of intracellularBipolar depressionMonoaminergic transmissionDepressive episodeDrug treatmentEffective treatmentTherapeutic interventionsIllnessPatientsSignificant tollGold standardTreatmentEpisodesDisordersDepressionInterventionRelative lackAntipsychoticsPharmacotherapy
2005
Lamotrigine in the treatment of bipolar disorder
Bhagwagar Z, Goodwin G. Lamotrigine in the treatment of bipolar disorder. Expert Opinion On Pharmacotherapy 2005, 6: 1401-1408. PMID: 16013989, DOI: 10.1517/14656566.6.8.1401.Peer-Reviewed Original ResearchConceptsBipolar disorderIncidence of rashCommon side effectsLong-term treatmentTreatment of epilepsyCareful prescribingPivotal trialsNovel anticonvulsant agentGlutamatergic functionMood disordersSide effectsPsychiatric conditionsAnticonvulsant agentsMode of actionIon channel conductanceDisordersLamotrigineLong-term basisTreatmentEfficacyPlaceboRashPrescribingHeadachePatients
2004
Bipolar disorder: the neglected psychosis
Bhagwagar Z, Goodwin G. Bipolar disorder: the neglected psychosis. Psychiatry 2004, 3: 67-70. DOI: 10.1383/psyt.3.10.67.52406.Peer-Reviewed Original ResearchBipolar disorderMainstay of treatmentNon-pharmacological interventionsSerious chronic illnessTraditional mood stabilizersLong-term treatmentMonoaminergic neurotransmitter systemsYears of lifeAtypical antipsychoticsMood stabilizersLifetime riskChronic illnessNeurotransmitter systemsNovel anticonvulsantMedical disordersEarly interventionAccurate diagnosisIllnessDisordersCognitive-behavioral approachDiagnosisInterventionTreatmentAntipsychoticsValproateInositol for depressive disorders
Taylor M, Wilder H, Bhagwagar Z, Geddes J. Inositol for depressive disorders. 2004, 2004: cd004049. PMID: 15106232, PMCID: PMC6984679, DOI: 10.1002/14651858.cd004049.pub2.Peer-Reviewed Original ResearchConceptsTreatment of depressionCochrane Controlled Trials RegisterControlled Trials RegisterTrials RegisterAdjunctive therapyDepressive disorderNeurosis Controlled Trials RegisterCochrane Collaboration DepressionAcceptability of treatmentDouble-blind designShort-term trialsAntidepressant medicationDATA COLLECTIONTherapeutic benefitAlternative treatmentReference listsAffective disordersEffective interventionsTerm trialsAdverse effectsTrialsPoor acceptabilityDepressionTreatmentDisorders
2002
The role of lithium in the treatment of bipolar depression
Bhagwagar Z, Goodwin G. The role of lithium in the treatment of bipolar depression. Clinical Neuroscience Research 2002, 2: 222-227. DOI: 10.1016/s1566-2772(02)00046-4.Peer-Reviewed Original Research
2001
Decreased sensitivity of 5-HT1D receptors in melancholic depression
Whale R, Clifford E, Bhagwagar Z, Cowen P. Decreased sensitivity of 5-HT1D receptors in melancholic depression. The British Journal Of Psychiatry 2001, 178: 454-457. PMID: 11331562, DOI: 10.1192/bjp.178.5.454.Peer-Reviewed Original ResearchConceptsSelective serotonin reuptake inhibitorsGrowth hormone responseGrowth hormone releaseSSRI treatmentMajor depressionHormone releaseMelancholic depressionHormone responseBrain serotonin functionSerotonin reuptake inhibitorsReuptake inhibitorsDepressive syndromeReceptor agonistReceptor subtypesSerotonin functionHealthy subjectsReceptor sensitivityPatientsControl groupMarked reductionZolmitriptanDepressionReceptorsTreatmentSelective ligands