Increase in Concentration of Waking Salivary Cortisol in Recovered Patients With Depression
Bhagwagar Z, Hafizi S, Cowen P. Increase in Concentration of Waking Salivary Cortisol in Recovered Patients With Depression. American Journal Of Psychiatry 2003, 160: 1890-1891. PMID: 14514508, DOI: 10.1176/appi.ajp.160.10.1890.Peer-Reviewed Original ResearchConceptsSalivary cortisol levelsCortisol levelsDepressed patientsAcute major depressionComorbid medical conditionsHPA axis abnormalitiesWithdrawal of medicationCoronary heart diseaseElevated plasma cortisol levelsHPA axis activityHealthy comparison subjectsPlasma cortisol levelsHealthy comparison groupClinical recoveryAxis abnormalitiesRecovered patientsAdrenal axisFurther episodesAxis activityHeart diseaseMajor depressionMedical conditionsComparison subjectsPatientsDepressed subjectsContrasting effects of citalopram and reboxetine on waking salivary cortisol
Harmer C, Bhagwagar Z, Shelley N, Cowen P. Contrasting effects of citalopram and reboxetine on waking salivary cortisol. Psychopharmacology 2003, 167: 112-114. PMID: 12605289, DOI: 10.1007/s00213-003-1417-y.Peer-Reviewed Original ResearchConceptsHPA axis activitySalivary cortisolAxis activitySelective noradrenaline re-uptake inhibitorNoradrenaline re-uptake inhibitorSelective serotonin re-uptake inhibitor citalopramConclusionsShort-term treatmentDifferent antidepressant medicationsHPA axis functionEffect of citalopramRe-uptake inhibitorsDouble-blind designShort-term treatmentBasal salivary cortisol levelsDiurnal salivary cortisolSalivary free cortisolSalivary cortisol levelsAntidepressant administrationRationaleAcute administrationReboxetine treatmentAntidepressant medicationAntidepressant treatmentAxis functionHPA axisAdrenal axis