Remission and relapse in major depression: a two-year prospective follow-up study
Ramana R, Paykel ES, Cooper Z, Hayhurst H, Saxty M, Surtees PG. Remission and relapse in major depression: a two-year prospective follow-up study. Psychological Medicine 1995, 25: 1161-1170. PMID: 8637946, DOI: 10.1017/s0033291700033134.Peer-Reviewed Original ResearchConceptsTwo-year prospective followMajor depressive subjectsGreater initial severityProspective followLate recurrencePoor outcomeWorse outcomesInitial severityDepressive subjectsMajor depressionRemissionAdequate treatmentRelapseGreater severityMonthsLonger durationDepressionSeveritySubjectsOutcomesTreatmentRecurrenceCohortFollowIllnessResidual symptoms after partial remission: an important outcome in depression
Paykel ES, Ramana R, Cooper Z, Hayhurst H, Kerr J, Barocka A. Residual symptoms after partial remission: an important outcome in depression. Psychological Medicine 1995, 25: 1171-1180. PMID: 8637947, DOI: 10.1017/s0033291700033146.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedDepressive DisorderHumansLongitudinal StudiesMiddle AgedRecurrenceRemission, SpontaneousConceptsResidual symptomsPartial remissionMajor depressionSevere initial illnessImportant adverse outcomesHamilton Depression ScaleTypical depressive symptomsInitial illnessEarly relapsePrior illnessAdverse outcomesIllness episodesDepression ScaleDrug treatmentLow doseDepressive symptomsSymptom presenceSymptomsRemissionDepressionWeak associationStrongest predictorIllnessMonthsImportant outcomes