Collaborative Survival Analysis on Predicting Alzheimer’s Disease Progression
Xu W, Wang S, Shen L, Zhao Y. Collaborative Survival Analysis on Predicting Alzheimer’s Disease Progression. Statistics In Biosciences 2024, 1-24. DOI: 10.1007/s12561-024-09459-0.Peer-Reviewed Original ResearchAlzheimer's diseaseGenes associated with neuronal developmentAlzheimer's Disease Neuroimaging InitiativeGenetic dataAlzheimer's disease progressionGenetic variationPhenotypic varianceAD progressionGenetic featuresNeuronal developmentGenetic biomarkersAlzheimerADNI databaseMild cognitive impairmentSNPsCanonical correlation analysisGenesStructural MRI scansCombination of brain imagingBrain imagingGeneticsProgression of mild cognitive impairmentAD literatureTime-to-event outcomesTime-to-event predictionsSelf‐reported hearing loss is associated with faster cognitive and functional decline but not diagnostic conversion in the ADNI cohort
Miller A, Sharp E, Wang S, Zhao Y, Mecca A, van Dyck C, O'Dell R, Initiative F. Self‐reported hearing loss is associated with faster cognitive and functional decline but not diagnostic conversion in the ADNI cohort. Alzheimer's & Dementia 2024, 20: 7847-7858. PMID: 39324520, PMCID: PMC11567835, DOI: 10.1002/alz.14252.Peer-Reviewed Original ResearchSelf-reported hearing lossFunctional Activities QuestionnaireHearing lossMild cognitive impairmentModifiable risk factorsMild cognitive impairment participantsFunctional declineImpairment diagnosisModified Preclinical Alzheimer Cognitive CompositeRate of functional declineRate of cognitive declinePreclinical Alzheimer Cognitive CompositeRisk factorsCognitive impairmentSignificant longitudinal associationsActivity QuestionnaireLongitudinal associationsAlzheimer's Disease Neuroimaging InitiativeLongitudinal relationshipCognitive compositeCN participantsIncreased riskCognitive declineParticipantsDiagnostic conversion