2024
Heritability and genetic contribution analysis of structural-functional coupling in human brain
Dai W, Zhang Z, Song P, Zhang H, Zhao Y. Heritability and genetic contribution analysis of structural-functional coupling in human brain. Imaging Neuroscience 2024, 2: 1-19. DOI: 10.1162/imag_a_00346.Peer-Reviewed Original ResearchSC-FCSC-FC couplingStructural connectivityHuman Connectome ProjectConnectome ProjectVisual cortexCouplingFunctional connectivityWhite matter structural connectivityCingulo-opercularDorsal attentionGenetic correlation analysisSpectrum of complex traitsAdolescent Brain Cognitive Development StudyFunctional networksComplex traitsGenetic lociCognitive Development StudyGenetic variationGenetic interplayMode networkStructural-functional couplingSpectraA Principled Framework to Assess the Information-Theoretic Fitness of Brain Functional Sub-Circuits
Duong-Tran D, Nguyen N, Mu S, Chen J, Bao J, Xu F, Garai S, Cadena-Pico J, Kaplan A, Chen T, Zhao Y, Shen L, Goñi J. A Principled Framework to Assess the Information-Theoretic Fitness of Brain Functional Sub-Circuits. Mathematics 2024, 12: 2967. PMID: 38979488, PMCID: PMC11230349, DOI: 10.3390/math12192967.Peer-Reviewed Original ResearchStochastic block modelMultiple levels of granularityLevels of granularityFunctional networksInformation-theoreticThreshold methodThreshold strategyFunctional connectomeSub-circuitsGranularityHuman brain connectomeNetworkHuman Connectome ProjectBlock modelBrain connectome analysisFunctional sub-circuitsTopological featuresFrameworkPrinciples frameworkConnectome ProjectBrain connectomeNetwork neuroscienceThreshold valueMultiple levelsPartitioning
2022
Bayesian network mediation analysis with application to the brain functional connectome
Zhao Y, Chen T, Cai J, Lichenstein S, Potenza M, Yip S. Bayesian network mediation analysis with application to the brain functional connectome. Statistics In Medicine 2022, 41: 3991-4005. PMID: 35795965, PMCID: PMC10131252, DOI: 10.1002/sim.9488.Peer-Reviewed Original ResearchConceptsStochastic block modelBayesian paradigmBrain functional connectomeBlock modelConnectivity weightsFunctional connectomeNetwork measurementsEffect componentApproach applicationBlock allocationOpioid abstinenceAnalytic approachNetwork neurosciencePractical illustrationTherapeutic interventionsMediation analysisNeural circuitsNetwork structureBrain functioningMediatorsFunctional networksFeature selectionApplicationsModelNetwork