2011
CaV1.2 Channel N-terminal Splice Variants Modulate Functional Surface Expression in Resistance Size Artery Smooth Muscle Cells*
Bannister J, Thomas-Gatewood C, Neeb Z, Adebiyi A, Cheng X, Jaggar J. CaV1.2 Channel N-terminal Splice Variants Modulate Functional Surface Expression in Resistance Size Artery Smooth Muscle Cells*. Journal Of Biological Chemistry 2011, 286: 15058-15066. PMID: 21357696, PMCID: PMC3083159, DOI: 10.1074/jbc.m110.182816.Peer-Reviewed Original ResearchConceptsArterial smooth muscle cellsSmooth muscle cellsMuscle cellsSurface expressionIntravascular pressureSmooth muscle-specific expressionArtery smooth muscle cellsDepolarization-induced vasoconstrictionHuman cerebral arteriesWhole-cell currentsReduced surface expressionLarge vasodilationCerebral arteryInflux pathwayVariety of stimuliCardiovascular systemFunctional surface expressionVasodilationProximal N-terminusReduced expressionMuscle-specific expressionE1CAuxiliary subunitsKnockdownPhysiological functions
2001
Inhibition of Ryanodine Binding to Sarcoplasmic Reticulum Vesicles of Cardiac Muscle by Zn2+ Ions
Wang H, Wei Q, Cheng X, Chen K, Zhu P. Inhibition of Ryanodine Binding to Sarcoplasmic Reticulum Vesicles of Cardiac Muscle by Zn2+ Ions. Cellular Physiology And Biochemistry 2001, 11: 83-92. PMID: 11275686, DOI: 10.1159/000047795.Peer-Reviewed Original ResearchConceptsInhibitory effectCardiac muscleModulators of RyRSarcoplasmic reticulumSkeletal muscleSarcoplasmic reticulum vesiclesMuscleScatchard analysisRyanodine receptorRyanodine bindingRyRsThiol-reducing agentsPhysiological significanceReticulum vesiclesHill coefficientObvious changeActivation siteMM dithiothreitol
2000
Biphasic modulation of ryanodine binding to sarcoplasmic reticulum vesicles of skeletal muscle by Zn2+ ions
XIA R, CHENG X, Hui W, CHEN K, WEI Q, ZHANG X, ZHU P. Biphasic modulation of ryanodine binding to sarcoplasmic reticulum vesicles of skeletal muscle by Zn2+ ions. Biochemical Journal 2000, 345: 279-286. PMID: 10620505, PMCID: PMC1220757, DOI: 10.1042/bj3450279.Peer-Reviewed Original ResearchConceptsSarcoplasmic reticulum vesiclesReticulum vesiclesBiphasic modulationSkeletal muscle ryanodine receptorPeak bindingInhibitory effectMuscle ryanodine receptorHeavy sarcoplasmic reticulum vesiclesSkeletal muscleScatchard analysisRyanodine receptorBiphasic time courseRyanodine bindingTime courseMicroMThiol-reducing agentsPhysiological significanceInactivation site