Featured Publications
Orbitofacial morphology changes with different suture synostoses in Crouzon syndrome
Lu X, Forte AJ, Junn A, Dinis J, Alperovich M, Alonso N, Persing JA. Orbitofacial morphology changes with different suture synostoses in Crouzon syndrome. Journal Of Cranio-Maxillofacial Surgery 2021, 50: 406-418. PMID: 35065874, DOI: 10.1016/j.jcms.2021.06.012.Peer-Reviewed Original ResearchConceptsCrouzon syndrome patientsSquamosal synostosisSyndrome patientsCT scanBicoronal synostosisCrouzon syndromeComputed tomography scanSoft tissue volumeType ISurgical interventionTomography scanNormal controlsOccipital expansionGlobe volumeCrouzon patientsSagittal synostosisPatientsAnteroposterior lengthSynostosisOrbital rimStatistical significanceTissue volumeSynostosesType IVType VGrowth patterns of the airway in Crouzon syndrome patients with different types of cranial vault suture synostosis
Lu X, Forte AJ, Wilson A, Park KE, Allam O, Alperovich M, Steinbacher DM, Tonello C, Alonso N, Persing JA. Growth patterns of the airway in Crouzon syndrome patients with different types of cranial vault suture synostosis. International Journal Of Oral And Maxillofacial Surgery 2020, 50: 924-932. PMID: 33384236, DOI: 10.1016/j.ijom.2020.11.023.Peer-Reviewed Original ResearchMeSH KeywordsCranial SuturesCraniofacial DysostosisCraniosynostosesFacial BonesHumansInfantSuturesTomography, X-Ray ComputedConceptsAirway volumeCrouzon syndrome patientsYears of ageNasal airwaySyndrome patientsCrouzon patientsPharyngeal airwayCrouzon syndromeSuture synostosisNasopharyngeal airway volumePharyngeal airway volumeNasal airway volumeType IComputed tomography scanType IIIBilateral coronal synostosisAirway compromiseRespiratory difficultyControl subjectsTomography scanAirwayPatientsPharyngeal volumeSagittal synostosisCoronal synostosisClassification of Subtypes of Crouzon Syndrome Based on the Type of Vault Suture Synostosis.
Lu X, Sawh-Martinez R, Forte AJ, Wu R, Cabrejo R, Wilson A, Steinbacher DM, Alperovich M, Alonso N, Persing JA. Classification of Subtypes of Crouzon Syndrome Based on the Type of Vault Suture Synostosis. Journal Of Craniofacial Surgery 2020, 31: 678-684. PMID: 32068731, DOI: 10.1097/scs.0000000000006173.Peer-Reviewed Original ResearchConceptsClass IIICrouzon syndromeClass IClass IISuture involvementSuture synostosisSimilar craniofacial characteristicsComputed tomography scanClassification of subtypesSurgical interventionMorphology of patientsAnatomic deformityTomography scanSurgical techniqueCT scanDifferent subtypesSagittal synostosisSyndromeClass IVPremature closureCraniofacial characteristicsSevere craniofacial malformationsCranial base lengthSynostosisDifferent pathologies
2021
Does different cranial suture synostosis influence orbit volume and morphology in Apert syndrome?
Lu X, Forte A, Alperovich M, Alonso N, Persing J. Does different cranial suture synostosis influence orbit volume and morphology in Apert syndrome? International Journal Of Oral And Maxillofacial Surgery 2021, 51: 338-346. PMID: 34400025, DOI: 10.1016/j.ijom.2021.07.019.Peer-Reviewed Original ResearchConceptsApert syndrome patientsSyndrome patientsBone volumeApert syndromeBicoronal synostosisType IType IIISuture synostosisComputed tomography scanType IIMaxillary bone volumeIndividualized surgical planningOrbital cavity volumeBilateral coronal synostosisTomography scanAnatomic basisBone malformationsSurgical planningSynostosisCoronal synostosisOrbital rimStatistical significanceOrbit volumePatientsSyndromeAberrant Morphologic Patterning of Combined Sagittal and Metopic Craniosynostosis
Dinis J, Junn A, Lu X, Lopez J, Persing J. Aberrant Morphologic Patterning of Combined Sagittal and Metopic Craniosynostosis. Journal Of Craniofacial Surgery 2021, 32: 2184-2185. PMID: 34183627, DOI: 10.1097/scs.0000000000007676.Peer-Reviewed Original ResearchCephalocranial Disproportionate Fossa Volume and Normal Skull Base Angle in Pfeiffer Syndrome.
Lu X, Forte AJ, Allam O, Park KE, Alperovich M, Steinbacher DM, Tonello C, Alonso N, Persing JA. Cephalocranial Disproportionate Fossa Volume and Normal Skull Base Angle in Pfeiffer Syndrome. Journal Of Craniofacial Surgery 2021, 32: 581-586. PMID: 33704985, DOI: 10.1097/scs.0000000000007203.Peer-Reviewed Original ResearchConceptsPfeiffer syndrome patientsMiddle cranial fossaCranial fossaSyndrome patientsFossa volumePfeiffer patientsSurgical interventionSuture synostosisPfeiffer syndromePreoperative CT scanPosterior cranial fossa volumeAnterior cranial fossaSkull base developmentSkull base angleClinical manifestationsCraniosynostosis disordersCT scanPosterior fossaNormal controlsAnatomic basisAnterior fossaPatientsSquamosal synostosisStructural abnormalitiesSubgroup comparisons
2020
Distinguishing Craniomorphometric Characteristics of Unilateral Lambdoid Craniosynostosis.
Allam O, Park KE, Pourtaheri N, Mozaffari MA, Smetona J, Lu X, Ahmad M, Persing JA, Alperovich M. Distinguishing Craniomorphometric Characteristics of Unilateral Lambdoid Craniosynostosis. Journal Of Craniofacial Surgery 2020, 32: 125-129. PMID: 33156173, DOI: 10.1097/scs.0000000000007098.Peer-Reviewed Original ResearchMeSH KeywordsCranial SuturesCraniosynostosesDiagnosis, DifferentialFemaleHumansInfantMaleMastoidTomography, X-Ray ComputedConceptsUnilateral lambdoid synostosisUL patientsDeformational plagiocephalySingle-suture nonsyndromic craniosynostosisPosterior deformational plagiocephalyUnilateral lambdoid craniosynostosisDP patientsClinical findingsPathological characteristicsRare formPatientsAnterior midlineLambdoid craniosynostosisMajority maleCT imagingLambdoid synostosisNonsyndromic craniosynostosisReliable indicatorSignificant differencesLambdoid sutureSide earCraniosynostosisScansEarPatient scansWhat Is the Difference in Cranial Base Morphology in Isolated and Syndromic Bicoronal Synostosis?
Lu X, Forte AJ, Wilson AT, Park KE, Allam O, Mozaffari MA, Alperovich M, Steinbacher DM, Alonso N, Persing JA. What Is the Difference in Cranial Base Morphology in Isolated and Syndromic Bicoronal Synostosis? Plastic & Reconstructive Surgery 2020, 146: 599-610. PMID: 32842109, DOI: 10.1097/prs.0000000000007068.Peer-Reviewed Original Research
2019
What Is the Skull Structure Influence of Squamosal Suture Synostosis in Nonsyndromic and Syndromic Crouzon Craniosynostosis?
Lu X, Chen G, Forte AJ, Cabrejo R, Singh A, Kyle G, Steinbacher DM, Alperovich M, Alonso N, Persing JA. What Is the Skull Structure Influence of Squamosal Suture Synostosis in Nonsyndromic and Syndromic Crouzon Craniosynostosis? Journal Of Craniofacial Surgery 2019, 30: 1671-1675. PMID: 30950948, DOI: 10.1097/scs.0000000000005396.Peer-Reviewed Original ResearchConceptsMiddle cranial fossaAnterior cranial fossaCranial fossaPosterior cranial fossaSquamosal synostosisFossa volumeCrouzon syndromeSquamosal suture synostosisComputed tomography scanCranial volumeNonsyndromic craniosynostosis patientsVolume reductionSevere volume reductionTomography scanNormal controlsMorphologic effectsCraniosynostosis patientsFossaPremature closureSyndromic conditionsSuture synostosisSyndromic synostosisFrankfort horizontal planeSynostosisThree-dimensional cephalometry